This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The age-adjusted prevalence of self-reported hypertension in adults in Arkansas increased from 22.8% to 28.9% over the time period 1993 to 2003. In certain areas, the rates are even higher, in Lee County in 2002, 38% of adults reported being told that they had hypertension. In 2001, the most recent year for which we have comparative mortality data, the age adjusted mortality rates for heart disease and stroke in Arkansas were 12% and 31% higher than the national average, and Arkansas had the highest stroke mortality rate in the nation. Despite the very high morbidity from hypertension related conditions, no data are available in Arkansas to show the prevalence of undiagnosed hypertension, or the degree to which persons with diagnosed hypertension have their blood pressure controlled to JNC-7 recommended levels. The Arkansas Minority Health Commission (AMHC) is developing a population-based representative household examination survey of blood pressure and cardiovascular disease risk factors in adults in Marianna, AR, to estimate the prevalence of undiagnosed hypertension, the prevalence of controlled and uncontrolled high blood pressure in those with diagnosed hypertension, and the association of other cardiovascular disease risk factors with hypertension. Participants in the examination survey will be asked to respond to an interviewer-administered questionnaire which asks about their medical history, health habits and behaviors, family history. In addition, an examination will include 6 measurements of blood pressure according to a standard protocol, as well as measurement of height, weight, waist circumference and percent body fat. Blood will be tested for plasma glucose, HbA1c, lipid panel, high-sensitivity C-reactive protein (CRP), hemoglobin, serum creatinine, cystatin C; urine will be tested for blood, and for albumin and creatinine concentration.
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