This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Children who snore are often seen by a doctor for a condition called Sleep Disordered Breathing (SDB). Testing for SDB is done with a test called a sleep study. One particular type of SDB is call Obstructive Sleep Apnea (OSA). Untreated OSA can cause restless sleep, behavior problems, poor school performance, and problems with growth. The usual treatment for OSA is a surgery called a Tonsillectomy and Adenoidectomy. Many people who have OSA also have asthma and/or allergies. We know that both asthma and OSA are more common in African-American children. In the city of Baltimore, up to 1 in 5 children have asthma which is much higher than the average number of children in the State of Maryland with asthma. The main reason we are doing this research study to see if asthma is more likely in children who have OSA . We are also trying to see if it is possible to get a 'sputum' sample from kids. Sputum is like spit but it comes from deep in the lungs. If we can collect sputum samples, we will look for certain kinds of allergic cells and chemicals in the sputum. Patients are usually scheduled for a sleep study because they snore and their doctor is concerned that they may have Obstructive Sleep Apnea. If the sleep study shows that patients do have Obstructive Sleep Apnea, a surgical procedure called a Tonsillectomy and Adenoidectomy may be indicated. The decision to have the sleep study and surgery is not part of this research study. Being part of this research project does not affect the patient's treatment of Obstructive Sleep Apnea.

Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
General Clinical Research Centers Program (M01)
Project #
5M01RR016500-05
Application #
7376973
Study Section
National Center for Research Resources Initial Review Group (RIRG)
Project Start
2006-03-01
Project End
2007-02-28
Budget Start
2006-03-01
Budget End
2007-02-28
Support Year
5
Fiscal Year
2006
Total Cost
$495
Indirect Cost
Name
University of Maryland Baltimore
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
188435911
City
Baltimore
State
MD
Country
United States
Zip Code
21201
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