This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We will study if the Laser Doppler Imaging Scanner gives precise measures so it can eventually be used to diagnose subjects with Raynaud s, especially those with Scleroderma. The Laser Doppler Imaging scanner is a tool to scan and take pictures of the skin and body to measure blood flow. It is used mostly in Europe and in some parts of the U.S. It has been used in a lot of medical specialties such as dermatology to evaluate skin diseases, in burns to asses the severity, in plastic surgery to assess skin graft success and in eye disease and eye surgery. In Rheumatologic diseases, it has been used to evaluate for blood flow in the hands and fingers in patients with Raynaud s phenomenon and Scleroderma. Researchers claim that it has shown to give precise measures of the finger blood flow in patients with Raynaud s who have been treated with medications to improve circulation.
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