This subproject is one of many research subprojects utilizing theresources provided by a Center grant funded by NIH/NCRR. The subproject andinvestigator (PI) may have received primary funding from another NIH source,and thus could be represented in other CRISP entries. The institution listed isfor the Center, which is not necessarily the institution for the investigator. Sleep disorders and insufficient sleep in adults are common and have been associated with serious sequelae including increased morbidity, affective disturbance, injury, and loss of productivity in the work place. The effects of insufficient sleep of pre-adolescents have only been addressed in a few studies. If the effects in children prove to be as far ranging as those documented in adults, sleep disturbance may interfefe with the development of cognitive, academic, and social skills and in hte developing capacity to regulate attention and emotion. Tobegin to elucidate these effects, a sleep restriction protocol will be used to evaluate children with obstructive sleep apnea syndrome (a common and serious sleep disorder) and in a healthy comparions group. The primary objetives of the study are: 1. Establish a methodology to measure the impact of insufficient sleep on children; 2. characterize the impact of insuffiencent sleep on specific cognitive domains and the regulation of affective and attentional state; 3. study the daytime sequelae of obstructive sleep apnea in children.
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