Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research and Development Contracts (N01)
Project #
N01AI072623-014
Application #
2296705
Study Section
Project Start
1986-10-16
Project End
1993-10-15
Budget Start
1988-08-15
Budget End
1988-09-20
Support Year
Fiscal Year
1988
Total Cost
Indirect Cost

  Institution

Name
Georgetown University
Department
Microbiology/Immun/Virology
Type
School of Medicine & Dentistry
DUNS #
049515844
City
Washington
State
DC
Country
United States
Zip Code
20057

  Publications

Korba, B E; Cote, P; Hornbuckle, W et al. (2000) Treatment of chronic woodchuck hepatitis virus infection in the Eastern woodchuck (Marmota monax) with nucleoside analogues is predictive of therapy for chronic hepatitis B virus infection in humans. Hepatology 31:1165-75
Korba, B E; Cote, P; Hornbuckle, W et al. (2000) Enhanced antiviral benefit of combination therapy with lamivudine and famciclovir against WHV replication in chronic WHV carrier woodchucks. Antiviral Res 45:19-32
Korba, B E; Cote, P; Hornbuckle, W et al. (2000) Enhanced antiviral benefit of combination therapy with lamivudine and alpha interferon against WHV replication in chronic carrier woodchucks. Antivir Ther 5:95-104
Chen, H S; Miller, R H; Hornbuckle, W E et al. (1998) Titration of recombinant woodchuck hepatitis virus DNA in adult woodchucks. J Med Virol 54:92-4
Hostetler, K Y; Beadle, J R; Kini, G D et al. (1997) Enhanced oral absorption and antiviral activity of 1-O-octadecyl-sn-glycero-3-phospho-acyclovir and related compounds in hepatitis B virus infection, in vitro. Biochem Pharmacol 53:1815-22
Korba, B E; Boyd, M R (1996) Penciclovir is a selective inhibitor of hepatitis B virus replication in cultured human hepatoblastoma cells. Antimicrob Agents Chemother 40:1282-4
Korba, B A; Xie, H; Wright, K N et al. (1996) Liver-targeted antiviral nucleosides: enhanced antiviral activity of phosphatidyl-dideoxyguanosine versus dideoxyguanosine in woodchuck hepatitis virus infection in vivo. Hepatology 23:958-63
Casey, J L; Gerin, J L (1995) Hepatitis D virus RNA editing: specific modification of adenosine in the antigenomic RNA. J Virol 69:7593-600
Korba, B E; Gerin, J L (1995) Antisense oligonucleotides are effective inhibitors of hepatitis B virus replication in vitro. Antiviral Res 28:225-42
Langley, R J; Hirsch, V M; O'Brien, S J et al. (1994) Nucleotide sequence analysis of puma lentivirus (PLV-14): genomic organization and relationship to other lentiviruses. Virology 202:853-64

Showing the most recent 10 out of 63 publications