The Drug Synthesis and Chemistry Branch (DS&CB) of the Developmental Therapeutics Program (DTP) of the Division of Cancer Treatment (DCT) of the National Cancer Institute (NCI) is seeking contractors with chemical synthesis expertise to synthesis a variety of compounds for evaluation as potential anticancer agents. The objectives of this project are to: synthesize congeners of synthetic compounds with confirmed activity; design and synthesize """"""""pro-drugs"""""""" and other compounds that possess elements of both congener and pro-drug; and synthesize compounds related to products of natural origin and other related heterocycles.
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