The investigator will isolate the prostate gland from rats and dogs and will evaluate the uptake of chromophores with different ionization constants using fluorescent confocal microscopy. The investigators will assess in vivo uptake of the chromophores and will compare in vitro and in vivo results. Intracellular compartmentalization will also be assessed.

Agency
National Institute of Health (NIH)
Institute
Division of Cancer Prevention And Control (NCI)
Type
Research and Development Contracts (N01)
Project #
N01CN095055-000
Application #
6154482
Study Section
Project Start
1999-09-30
Project End
Budget Start
1999-09-30
Budget End
2001-03-29
Support Year
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Illinois at Chicago
Department
Pharmacology
Type
Schools of Medicine
DUNS #
121911077
City
Chicago
State
IL
Country
United States
Zip Code
60612
Lyubimov, Alexander V; Carr, Seraya N; Brown, Alan P et al. (2005) Evaluation of hydrogen ion concentrations in prostates from rats and dogs using fluorescent confocal microscopy. J Photochem Photobiol B 80:225-34