Abstract

The Viral Studies Section (VSS), Viral Epidemiology Branch (VEB), Epidemiology & Biostatistics Program (EBP), Division of Cancer Etiology (DCE), National Cancer Institute (NCI), is continuing the conduct of this study to define, through a series of epidemiologic, clinical and experimental studies, the distribution and determinants of HTLV infection and the possible role of HTLV as a cause of cancer. An important future direction is to follow-up infection for both HTLV and HIV, and use these high risk populations to define the natural history and pathogenesis of viral-related outcomes.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Division of Cancer Epidemiology And Genetics (NCI)
Type
Research and Development Contracts (N01)
Project #
N01CP040548-023
Application #
6338350
Study Section
Project Start
1994-01-29
Project End
2001-05-15
Budget Start
2000-08-02
Budget End
2001-02-28
Support Year
Fiscal Year
2000
Total Cost
$470,000
Indirect Cost

  Institution

Name
University of the West Indies
Department
Type
DUNS #
City
Kingston
State
Country
Jamaica
Zip Code

  Publications

Goedert, James J; Li, Hong-Chuan; Gao, Xiao-Jiang et al. (2007) Risk of human T-lymphotropic virus type I-associated diseases in Jamaica with common HLA types. Int J Cancer 121:1092-7
Biggar, Robert J; Ng, Jennifer; Kim, Norma et al. (2006) Human leukocyte antigen concordance and the transmission risk via breast-feeding of human T cell lymphotropic virus type I. J Infect Dis 193:277-82
Tseng, Fan-Chen; Brown, Elizabeth E; Maiese, Eric M et al. (2006) Polymorphisms in cytokine genes and risk of Helicobacter pylori infection among Jamaican children. Helicobacter 11:425-30
Maloney, Elizabeth Margaret; Yamano, Yoshihisa; Vanveldhuisen, Paul C et al. (2006) Natural history of viral markers in children infected with human T lymphotropic virus type I in Jamaica. J Infect Dis 194:552-60
Li, Hong-Chuan; Biggar, Robert J; Miley, Wendell J et al. (2004) Provirus load in breast milk and risk of mother-to-child transmission of human T lymphotropic virus type I. J Infect Dis 190:1275-8
Maloney, Elizabeth M; Nagai, Masahiro; Hisada, Michie et al. (2004) Prediagnostic human T lymphotropic virus type I provirus loads were highest in Jamaican children who developed seborrheic dermatitis and severe anemia. J Infect Dis 189:41-5
Hisada, Michie; Stuver, Sherri O; Okayama, Akihiko et al. (2004) Persistent paradox of natural history of human T lymphotropic virus type I: parallel analyses of Japanese and Jamaican carriers. J Infect Dis 190:1605-9
Hisada, Michie; Maloney, Elizabeth M; Sawada, Takashi et al. (2002) Virus markers associated with vertical transmission of human T lymphotropic virus type 1 in Jamaica. Clin Infect Dis 34:1551-7
Maloney, E M; Hisada, M; Palmer, P et al. (2000) Human T cell lymphotropic virus type I-associated infective dermatitis in Jamaica: a case report of clinical and biologic correlates. Pediatr Infect Dis J 19:560-5
Manns, A; Strickler, H D; Wikktor, S Z et al. (1999) Low incidence of human papillomavirus type 16 antibody seroconversion in young children. Pediatr Infect Dis J 18:833-5

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