Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research and Development Contracts (N01)
Project #
N01DA001101-000
Application #
6359409
Study Section
Project Start
2000-09-20
Project End
2002-09-19
Budget Start
2000-09-20
Budget End
2001-09-19
Support Year
Fiscal Year
2000
Total Cost
$321,947
Indirect Cost
Name
Management Assistance Corporation
Department
Type
DUNS #
City
Fairfax
State
VA
Country
United States
Zip Code
22031
Kim, Youseung; Maciag, Anna E; Cao, Zhao et al. (2015) PABA/NO lead optimization: Improved targeting of cytotoxicity to glutathione S-transferase P1-overexpressing cancer cells. Bioorg Med Chem 23:4980-8
Keck, Thomas M; Banala, Ashwini K; Slack, Rachel D et al. (2015) Using click chemistry toward novel 1,2,3-triazole-linked dopamine D3 receptor ligands. Bioorg Med Chem 23:4000-12
Iyer, Malliga R; Cinar, Resat; Liu, Jie et al. (2015) Structural Basis of Species-Dependent Differential Affinity of 6-Alkoxy-5-Aryl-3-Pyridinecarboxamide Cannabinoid-1 Receptor Antagonists. Mol Pharmacol 88:238-44
Jalah, Rashmi; Torres, Oscar B; Mayorov, Alexander V et al. (2015) Efficacy, but not antibody titer or affinity, of a heroin hapten conjugate vaccine correlates with increasing hapten densities on tetanus toxoid, but not on CRM197 carriers. Bioconjug Chem 26:1041-53
Suzuki, Masaki; Deschamps, Jeffrey R; Jacobson, Arthur E et al. (2015) Chiral resolution and absolute configuration of the enantiomers of the psychoactive ""designer drug"" 3,4-methylenedioxypyrovalerone. Chirality 27:287-93
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Hassler, Carla; Zhang, Yanan; Gilmour, Brian et al. (2014) Identification of neuropeptide S antagonists: structure-activity relationship studies, X-ray crystallography, and in vivo evaluation. ACS Chem Neurosci 5:731-44
Rallapalli, Sundari K; Namjoshi, Ojas A; Tiruveedhula, V V N Phani Babu et al. (2014) Stereospecific total synthesis of the indole alkaloid ervincidine. Establishment of the C-6 hydroxyl stereochemistry. J Org Chem 79:3776-80
Selfridge, Brandon R; Deschamps, Jeffrey R; Jacobson, Arthur E et al. (2014) Synthesis of enantiopure 10-nornaltrexones in the search for Toll-like receptor 4 antagonists and opioid ligands. J Org Chem 79:5007-18
Thakur, Ganesh A; Kulkarni, Abhijit R; Deschamps, Jeffrey R et al. (2013) Expeditious synthesis, enantiomeric resolution, and enantiomer functional characterization of (4-(4-bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide (4BP-TQS): an allosteric agonist-positive allosteric modulator of ?7 nicotinic ac J Med Chem 56:8943-7

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