Abstract

Perform work as a clinical center in a multicenter clinical trial to determine the effects of early intervention for chronic obstructive pulmonary disease in cigarette smokers with mild airways dysfunction.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Division of Lung Diseases (NHLBI)
Type
Research and Development Contracts (N01)
Project #
N01HR046014-014
Application #
2317089
Study Section
Project Start
1984-09-30
Project End
1992-03-29
Budget Start
1989-11-28
Budget End
1990-09-30
Support Year
Fiscal Year
1990
Total Cost
Indirect Cost

  Institution

Name
University of Utah
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Salt Lake City
State
UT
Country
United States
Zip Code
84112

  Publications

Baker, Timothy B; Weiss, Robert B; Bolt, Daniel et al. (2009) Human neuronal acetylcholine receptor A5-A3-B4 haplotypes are associated with multiple nicotine dependence phenotypes. Nicotine Tob Res 11:785-96
Weiss, Robert B; Baker, Timothy B; Cannon, Dale S et al. (2008) A candidate gene approach identifies the CHRNA5-A3-B4 region as a risk factor for age-dependent nicotine addiction. PLoS Genet 4:e1000125
Wise, Robert A; Kanner, Richard E; Lindgren, Paula et al. (2003) The effect of smoking intervention and an inhaled bronchodilator on airways reactivity in COPD: the Lung Health Study. Chest 124:449-58
Kanner, R E; Anthonisen, N R; Connett, J E et al. (2001) Lower respiratory illnesses promote FEV(1) decline in current smokers but not ex-smokers with mild chronic obstructive pulmonary disease: results from the lung health study. Am J Respir Crit Care Med 164:358-64
Kanner, R E; Connett, J E; Williams, D E et al. (1999) Effects of randomized assignment to a smoking cessation intervention and changes in smoking habits on respiratory symptoms in smokers with early chronic obstructive pulmonary disease: the Lung Health Study. Am J Med 106:410-6
Kanner, R E (1996) Early intervention in chronic obstructive pulmonary disease. A review of the Lung Health Study results. Med Clin North Am 80:523-47
Kanner, R E; Connett, J E; Altose, M D et al. (1994) Gender difference in airway hyperresponsiveness in smokers with mild COPD. The Lung Health Study. Am J Respir Crit Care Med 150:956-61