Abstract

The objectives of each Vanguard Clinical Center is to cooperate with the Clinical Coordinating Center in developing, implementing and refining the overall program to ensure its feasibility and optimize it operationally before the additional Clinical Centers commence recruitment. The Vanguard Clinical Centers are to assist in the development, testing and implementation of the forms/questionnaires and procedures needed to recruit a group of postmenopausal U.S. women age 50-79, randomize them to a number of interventions, ensure adherence and adequate follow-up, and collect and transmit data and biological samples as needed for the ascertainment of the outcomes of the Clinical Trial and Observational Study.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Women'S Health Initiative - Office of The Director Nih (WH)
Type
Research and Development Contracts (N01)
Project #
N01WH032100-006
Application #
2326491
Study Section
Project Start
1993-03-15
Project End
2005-09-14
Budget Start
1995-06-26
Budget End
1998-05-14
Support Year
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
Fred Hutchinson Cancer Research Center
Department
Type
DUNS #
075524595
City
Seattle
State
WA
Country
United States
Zip Code
98109

  Publications

Gong, J; Nishimura, K K; Fernandez-Rhodes, L et al. (2018) Trans-ethnic analysis of metabochip data identifies two new loci associated with BMI. Int J Obes (Lond) 42:384-390
Jo Hodonsky, Chani; Schurmann, Claudia; Schick, Ursula M et al. (2018) Generalization and fine mapping of red blood cell trait genetic associations to multi-ethnic populations: The PAGE Study. Am J Hematol :
Yoneyama, S; Yao, J; Guo, X et al. (2017) Generalization and fine mapping of European ancestry-based central adiposity variants in African ancestry populations. Int J Obes (Lond) 41:324-331
Kato, Ikuko; Lane, Dorothy; Womack, Catherine R et al. (2017) Interaction between Nonsteroidal Anti-inflammatory Drugs and Low-fat Dietary Intervention on Colorectal Cancer Incidence; the Women's Health Initiative (WHI) Dietary Modification Trial. J Am Coll Nutr 36:462-469
Kraja, Aldi T; Cook, James P; Warren, Helen R et al. (2017) New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475?000 Individuals. Circ Cardiovasc Genet 10:
Zaslavsky, O; Rillamas-Sun, E; Li, W et al. (2017) Association of Dynamics in Lean and Fat Mass Measures with Mortality in Frail Older Women. J Nutr Health Aging 21:112-119
Bao, Ying; Prescott, Jennifer; Yuan, Chen et al. (2017) Leucocyte telomere length, genetic variants at the TERT gene region and risk of pancreatic cancer. Gut 66:1116-1122
Chlebowski, Rowan T; Barrington, Wendy; Aragaki, Aaron K et al. (2017) Estrogen alone and health outcomes in black women by African ancestry: a secondary analyses of a randomized controlled trial. Menopause 24:133-141
Chlebowski, R T; Anderson, G L; Sarto, G E et al. (2016) Continuous Combined Estrogen Plus Progestin and Endometrial Cancer: The Women's Health Initiative Randomized Trial. J Natl Cancer Inst 108:
Assaf, Annlouise R; Beresford, Shirley A A; Risica, Patricia Markham et al. (2016) Low-Fat Dietary Pattern Intervention and Health-Related Quality of Life: The Women's Health Initiative Randomized Controlled Dietary Modification Trial. J Acad Nutr Diet 116:259-71

Showing the most recent 10 out of 230 publications