Abstract

The objectives of each Vanguard Clinical Center is to cooperate with the Clinical Coordinating Center in developing, implementing and refining the overall program to ensure its feasibility and optimize it operationally before the additional Clinical Centers commence recruitment. The Vanguard Clinical Centers are to assist in the development, testing and implementation of the forms/questionnaires and procedures needed to recruit a group of postmenopausal U.S. women age 50-79, randomize them to a number of interventions, ensure adherence and adequate follow-up, and collect and transmit data and biological samples as needed for the ascertainment of the outcomes of the Clinical Trial and Observational Study.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
Women'S Health Initiative - Office of The Director Nih (WH)
Type
Research and Development Contracts (N01)
Project #
N01WH032106-003
Application #
2326532
Study Section
Project Start
1993-03-15
Project End
2005-09-14
Budget Start
1993-09-30
Budget End
1996-08-16
Support Year
Fiscal Year
1993
Total Cost
Indirect Cost

  Institution

Name
Wake Forest University Health Sciences
Department
Public Health & Prev Medicine
Type
Schools of Medicine
DUNS #
041418799
City
Winston-Salem
State
NC
Country
United States
Zip Code
27106

  Publications

Gong, J; Nishimura, K K; Fernandez-Rhodes, L et al. (2018) Trans-ethnic analysis of metabochip data identifies two new loci associated with BMI. Int J Obes (Lond) 42:384-390
Jo Hodonsky, Chani; Schurmann, Claudia; Schick, Ursula M et al. (2018) Generalization and fine mapping of red blood cell trait genetic associations to multi-ethnic populations: The PAGE Study. Am J Hematol :
Kato, Ikuko; Lane, Dorothy; Womack, Catherine R et al. (2017) Interaction between Nonsteroidal Anti-inflammatory Drugs and Low-fat Dietary Intervention on Colorectal Cancer Incidence; the Women's Health Initiative (WHI) Dietary Modification Trial. J Am Coll Nutr 36:462-469
Zaslavsky, Oleg; Woods, Nancy F; LaCroix, Andrea Z et al. (2016) Identification of Risk Factors for Mortality and Poor-Quality-of-Life Survival in Frail Older Women Participating in the Women's Health Initiative Observational Study. J Am Geriatr Soc 64:831-7
Ehret, Georg B (see original citation for additional authors) (2016) The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nat Genet 48:1171-1184
Klimentidis, Yann C; Bea, Jennifer W; Thompson, Patricia et al. (2016) Genetic Variant in ACVR2B Is Associated with Lean Mass. Med Sci Sports Exerc 48:1270-5
Smith, Caren E; Coltell, Oscar; Sorlí, Jose V et al. (2016) Associations of the MCM6-rs3754686 proxy for milk intake in Mediterranean and American populations with cardiovascular biomarkers, disease and mortality: Mendelian randomization. Sci Rep 6:33188
Klimentidis, Y C; Arora, A; Chougule, A et al. (2016) FTO association and interaction with time spent sitting. Int J Obes (Lond) 40:411-6
Siegel, Rebecca L; Jacobs, Eric J; Newton, Christina C et al. (2015) Deaths Due to Cigarette Smoking for 12 Smoking-Related Cancers in the United States. JAMA Intern Med 175:1574-6
Gangwisch, James E; Hale, Lauren; Garcia, Lorena et al. (2015) High glycemic index diet as a risk factor for depression: analyses from the Women's Health Initiative. Am J Clin Nutr 102:454-63

Showing the most recent 10 out of 102 publications