The purpose of this contract is to conduct studies which will help the National Toxicology Program (NTP) in the toxicologic characterization associated with developmental exposre to a variety of chemicals on the Developmental, Neurobehavioral and Immunologic Function. The following studies have been initiated: (1)A definitive study to evaluate Neurobehavioral and immunologic function in Sprague Dawley rats exposed to 3,3',4,4'-tetrachloroazobenzene (2) Study to evaluate preimplantation loss following administation of 3,3',4,4'-tetrachloroazobenzene in Sprague Dawley rats.