The function of the Animal Core is to produce and maintain all of the animals required for the scientific projects for this and several other program project grants. The specific services of the Animal Core personnel include: 1) Production of transgenic and knockout mice, 2) Production of large volumes of scrapie-infected hamster brains for purification, 3) Performing experimental inoculations, neurologic scoring of animals, data collection, and tissue collection, 4) Providing transportation of animals and tissues between the laboratory and the animal facility; 5) Production of antibodies in mice and rabbits for experimental use, 6) Providing all animal care and veterinary care. The Animal Core operates in two purpose-build facilities in the Hunter's Point area of San Francisco, approximately 12 miles from the main UCSF campus. Its activities are directed by Dr. Prusiner and Dr. Marilyn Torchia, a laboratory animal veterinarian. Building 830B is a new nine room transgenic mouse breeding facility which houses or large breeding colony. Building 830 houses all the experimental animals in 21 rooms, under BSL 2 and 3 biocontainment.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Program Projects (P01)
Project #
5P01AG002132-20
Application #
6299219
Study Section
Project Start
2000-02-01
Project End
2000-12-31
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
20
Fiscal Year
2000
Total Cost
$444,200
Indirect Cost
Name
University of California San Francisco
Department
Type
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
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