Difficulty in rising from a chair is common in older adults and is associated with an increased risk for falls. Compared to standard functional assessment techniques, we will use a more quantitative approach. This approach will: improve the assessment of both mild to moderate dysfunction and changing functional status; help clarify relationships among aging, impairment, and disability; and be useful in the design of more effective interventions. The overall objectives of Project 3 are to quantify the effects of age, functional disability, and the presence of Parkinson's disease on chair rise biomechanics. Subjects will be recruited based on their chair rise performance in Project 1 (Lo-tech Tasks), to perform similar chair rise tasks as part of the Hi-tech Analyses of Lo-tech tasks. In the second part of Project 3, the Hi-tech Tasks, a separate subject group will be recruited to perform a series of Ordered Chair Rise Tasks. Designed to vary substantially in difficulty, the Ordered Chair Rise Tasks consist of controlled rises under conditions that differ in hand and foot support, seat height, and rise speed. As another part of the other Hi-tech Tasks, a healthy older adult group will perform a series of Unordered Chair Rise Tasks, designed to examine the contribution of sagittal asymmetry to rising from a chair. We will measure subject anthropometry, body segment kinematics and external support reactions. Using a biomechanical model, these data will be used to conduct inverse dynamics analyses that will provide the peak joint torque strengths used. We will compare joint motions and joint torques used in the chair mobility tasks with clinical measures of joint range of motion and muscular strength available. Finally, we will examine the relationships among chair rise task success, the joint ranges of motion and torque strengths used when they succeed, and: (1) physical abilities such as joint strength; and (2) neuropsychological measures such as fear of failing. Understanding how rising from a chair is affected by aging, neuropsychological status, and physical impairment will likely improve assessment and intervention. A biomechanical analysis of different task conditions can demonstrate the relationship between required joint range of motion and strength and conditions leading to successful rising from a chair. Finally, deficits in Parkinson's disease fit well with our paradigm of studying the effect of neuropsychological and physical components on the biomechanical parameters of mobility.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Program Projects (P01)
Project #
3P01AG010542-04S1
Application #
6234392
Study Section
Project Start
1997-06-01
Project End
1998-03-31
Budget Start
1996-10-01
Budget End
1997-09-30
Support Year
4
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Type
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Votruba, Kristen L; Persad, Carol; Giordani, Bruno (2016) Cognitive Deficits in Healthy Elderly Population With ""Normal"" Scores on the Mini-Mental State Examination. J Geriatr Psychiatry Neurol 29:126-32
Albin, Roger L; Burke, James F; Koeppe, Robert A et al. (2013) Assessing mild cognitive impairment with amyloid and dopamine terminal molecular imaging. J Nucl Med 54:887-93
Hernandez, Manuel E; Goldberg, Allon; Alexander, Neil B (2010) Decreased muscle strength relates to self-reported stooping, crouching, or kneeling difficulty in older adults. Phys Ther 90:67-74
Kim, Kyu-Jung; Ashton-Miller, James A (2009) Segmental dynamics of forward fall arrests: a system identification approach. Clin Biomech (Bristol, Avon) 24:348-54
Schulz, Brian W; Ashton-Miller, James A; Alexander, Neil B (2008) The effects of age and step length on joint kinematics and kinetics of large out-and-back steps. Clin Biomech (Bristol, Avon) 23:609-18
Schulz, Brian W; Ashton-Miller, James A; Alexander, Neil B (2007) Maximum step length: relationships to age and knee and hip extensor capacities. Clin Biomech (Bristol, Avon) 22:689-96
Schulz, Brian W; Ashton-Miller, James A; Alexander, Neil B (2007) A kinematic analysis of the rapid step test in balance-impaired and unimpaired older women. Gait Posture 25:515-22
Murphy, Susan L; Gretebeck, Kimberlee A; Alexander, Neil B (2007) The bath environment, the bathing task, and the older adult: a review and future directions for bathing disability research. Disabil Rehabil 29:1067-75
Ahmed, Alaa A; Ashton-Miller, James A (2007) On use of a nominal internal model to detect a loss of balance in a maximal forward reach. J Neurophysiol 97:2439-47
Schulz, Brian W; Ashton-Miller, James A; Alexander, Neil B (2006) Can initial and additional compensatory steps be predicted in young, older, and balance-impaired older females in response to anterior and posterior waist pulls while standing? J Biomech 39:1444-53

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