The goal of this project is to improve our knowledge of, and ability to measure, adult mortality in the developing world. Many developing countries lack conventional data sources permitting the regular measurement of mortality. Valid substitute methods for measuring mortality in childhood have been developed, and applied across the majority of developing countries. Success with development of substitute methods for adult mortality has been more limited, and no cross-national comparative reviews of age patterns and trends have been carried out, despite the fact that extensive data exist. This project will compile data sets relevant to the measurement of adult mortality for selected countries representing all regions of the developing world. We will evaluate the data sets and carry out adjustments as necessary, explore and quantify the performance of the methodologies available for evaluating such data sets and deriving mortality estimates from them, and develop new methodologies as necessary to improve estimation validity. Standard methods will be developed to assess the uncertainty affecting all estimates, and to define plausible ranges around observed mortality rates within which true rates are expected to lie. The validated data will then be used to compute life stables for the selected countries for different time points. A web-accessible data base including both raw data and final life tables will be created in parallel with the existing Berkeley Mortality questions: (a) how do patterns and trends of mortality in LDCs today compare with the historical experience of now- developed countries as observed in the BMD? (B) what has been the impact of economic reversals on mortality trends? And (c) how large has been the mortality impact of the HIV/AIDS epidemic? The mortality information for selected countries will also be used as a basis for developing region-specific distributions of deaths by age as a key input to studying burden of disease.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Program Projects (P01)
Project #
3P01AG017625-03S2
Application #
6662725
Study Section
Special Emphasis Panel (ZAG1)
Project Start
2002-09-30
Project End
2003-08-31
Budget Start
Budget End
Support Year
3
Fiscal Year
2002
Total Cost
$180,480
Indirect Cost
Name
Harvard University
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02115
Prospective Studies Collaboration and Asia Pacific Cohort Studies Collaboration (2018) Sex-specific relevance of diabetes to occlusive vascular and other mortality: a collaborative meta-analysis of individual data from 980?793 adults from 68 prospective studies. Lancet Diabetes Endocrinol 6:538-546
Akgun, S; Colak, M; Bakar, C (2012) Identifying and verifying causes of death in Turkey: National verbal autopsy survey. Public Health 126:150-8
Fang, Margaret C; Cutler, David M; Rosen, Allison B (2010) Trends in thrombolytic use for ischemic stroke in the United States. J Hosp Med 5:406-9
Prospective Studies Collaboration; Whitlock, Gary; Lewington, Sarah et al. (2009) Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies. Lancet 373:1083-96
Salomon, Joshua A; Nordhagen, Stella; Oza, Shefali et al. (2009) Are Americans feeling less healthy? The puzzle of trends in self-rated health. Am J Epidemiol 170:343-51
Stewart, Susan T; Woodward, Rebecca M; Rosen, Allison B et al. (2008) The impact of symptoms and impairments on overall health in US national health data. Med Care 46:954-62
Ikeda, Nayu; Gakidou, Emmanuela; Hasegawa, Toshihiko et al. (2008) Understanding the decline of mean systolic blood pressure in Japan: an analysis of pooled data from the National Nutrition Survey, 1986-2002. Bull World Health Organ 86:978-88
Wan, Xia; Wang, Li-Jun; Wang, Jun-Fang et al. (2008) Validity of diagnostic evidence for deceased cases in hospitals. Biomed Environ Sci 21:247-52
Gakidou, Emmanuela; Vayena, Effy (2007) Use of modern contraception by the poor is falling behind. PLoS Med 4:e31
Wang, Lijun; Yang, Gonghuan; Jiemin, Ma et al. (2007) Evaluation of the quality of cause of death statistics in rural China using verbal autopsies. J Epidemiol Community Health 61:519-26

Showing the most recent 10 out of 74 publications