The Administrative Core will manage the overall progress of the Program Project with the ultimate goal of defining the neurobiological basis of the therapeutic window of opportunity for estrogen and progesterone. The Administrative Core will: 1) hold overall responsibility for the administration of the program project, 2) manage the fiscal aspects of the Program Project, including the set up of project and core accounts, the appointment of new employees and re-appointment of existing personnel to the program accounts, reconciling accounts, reporting budgets to investigators, ordering of reagents and supplies, tracking orders and reporting expenditures to the UNT Health Science Center as well as NIA personnel, 3) manage the interactions between projects and cores, provide statistical support for all projects, and procure and distribute human tissue to the projects, and 4) foster an environment for the intellectual interactions of program investigators and between investigators at the UNT Health Science Center community, and with the research community at large.

Public Health Relevance

The successful interactions among Projects and Cores have, and will continue to be monitored and managed by the Administrative Core through regular meetings/teleconferences. In addition, the Administrative Core will also help shape the long-term goal of identifying improved or novel therapeutic strategies for treating age-associated disorders associated with the menopause and post-menopausal period, including Alzheimer's disease.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Program Projects (P01)
Project #
5P01AG027956-06
Application #
8589548
Study Section
Special Emphasis Panel (ZAG1-ZIJ-9)
Project Start
Project End
Budget Start
2013-12-01
Budget End
2014-11-30
Support Year
6
Fiscal Year
2014
Total Cost
$91,007
Indirect Cost
$28,244
Name
University of North Texas
Department
Type
DUNS #
110091808
City
Fort Worth
State
TX
Country
United States
Zip Code
76107
Nguyen, Trinh; Su, Chang; Singh, Meharvan (2018) Let-7i inhibition enhances progesterone-induced functional recovery in a mouse model of ischemia. Proc Natl Acad Sci U S A 115:E9668-E9677
Izurieta Munoz, Haydee; Gonzales, Eric B; Sumien, Nathalie (2018) Effects of creatine supplementation on nociception in young male and female mice. Pharmacol Rep 70:316-321
Montgomery, Christa L; Johnson, Heather M; Johnston, Thomas P et al. (2018) Mechanisms Underlying Early-Stage Changes in Visual Performance and Retina Function After Experimental Induction of Sustained Dyslipidemia. Neurochem Res 43:1500-1510
Grillo, Stephanie L; Montgomery, Christa L; Johnson, Heather M et al. (2018) Quantification of Changes in Visual Function During Disease Development in a Mouse Model of Pigmentary Glaucoma. J Glaucoma 27:828-841
Mock, J Thomas; Knight, Sherilynn G; Vann, Philip H et al. (2018) Gait Analyses in Mice: Effects of Age and Glutathione Deficiency. Aging Dis 9:634-646
Grillo, Michael A; Grillo, Stephanie L; Gerdes, Bryan C et al. (2018) Control of Neuronal Ryanodine Receptor-Mediated Calcium Signaling by Calsenilin. Mol Neurobiol :
Kaja, Simon; Payne, Andrew J; Naumchuk, Yuliya et al. (2017) Quantification of Lactate Dehydrogenase for Cell Viability Testing Using Cell Lines and Primary Cultured Astrocytes. Curr Protoc Toxicol 72:2.26.1-2.26.10
Gonzales, Eric B; Sumien, Nathalie (2017) Acidity and Acid-Sensing Ion Channels in the Normal and Alzheimer's Disease Brain. J Alzheimers Dis 57:1137-1144
Engler-Chiurazzi, E B; Brown, C M; Povroznik, J M et al. (2017) Estrogens as neuroprotectants: Estrogenic actions in the context of cognitive aging and brain injury. Prog Neurobiol 157:188-211
Engler-Chiurazzi, Elizabeth B; Covey, Douglas F; Simpkins, James W (2017) A novel mechanism of non-feminizing estrogens in neuroprotection. Exp Gerontol 94:99-102

Showing the most recent 10 out of 132 publications