This program project will establish, administer, and facilitate joint research activity across the lALSA and HALCyon research networks, involving key investigators and research teams from over 40 major longitudinal studies on adult development and aging. This Administrative Core will exercise overall coordination of the program project, including the development and maintenance of infrastructure, coordination among projects and cores, and provision of overall grants management. Each of the Subprojects in this proposed program emphasizes critical substantive issues in the study of aging-related changes: the administrative core will serve to facilitate synergy across these Subprojects and Cores. A vital function of this application is to develop further, maintain, and make use of an infrastructure for collaborative analysis of international longitudinal study data and facilitate broad dissemination of analytical and substantive knowledge to gerontological researchers. This Core will be responsible for planning of working meetings at national and international conferences to provide a forum for the dissemination and discussion of results and to act as a catalyst for the further development and analysis of affiliated studies. In addition, The Administrative Core will encourage early career investigators (including graduate students and postdoctoral fellows) to be involved in lALSA/HALCyon projects, obtain research training, and present results at annual meetings.

Public Health Relevance

This research program will advance current scientific priorities for integrative, interdisciplinary, and cross- national approaches to research on aging, cognition, personality, and health by making optimal use of major longitudinal studies on aging in direct collaboration with the principal research teams. CoreA is responsible for overall management of this program project that is based on a large collaborative research network.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Research Program Projects (P01)
Project #
5P01AG043362-05
Application #
9242544
Study Section
Special Emphasis Panel (ZAG1-ZIJ-9)
Project Start
Project End
2019-02-28
Budget Start
2017-03-01
Budget End
2018-02-28
Support Year
5
Fiscal Year
2017
Total Cost
$250,529
Indirect Cost
$87,848
Name
Oregon Health and Science University
Department
Type
Domestic Higher Education
DUNS #
096997515
City
Portland
State
OR
Country
United States
Zip Code
97239
Nguyen, Madeline T; Mattek, Nora; Woltjer, Randy et al. (2018) Pathologies Underlying Longitudinal Cognitive Decline in the Oldest Old. Alzheimer Dis Assoc Disord 32:265-269
Rawle, Mark James; Davis, Daniel; Bendayan, Rebecca et al. (2018) Apolipoprotein-E (Apoe) ?4 and cognitive decline over the adult life course. Transl Psychiatry 8:18
Karr, Justin E; Areshenkoff, Corson N; Rast, Philippe et al. (2018) The unity and diversity of executive functions: A systematic review and re-analysis of latent variable studies. Psychol Bull 144:1147-1185
Karr, Justin E; Graham, Raquel B; Hofer, Scott M et al. (2018) When does cognitive decline begin? A systematic review of change point studies on accelerated decline in cognitive and neurological outcomes preceding mild cognitive impairment, dementia, and death. Psychol Aging 33:195-218
Weston, Sara J; Hill, Patrick L; Edmonds, Grant W et al. (2018) No Evidence of ""healthy neuroticism"" in the Hawaii Personality and Health Cohort. Ann Behav Med :
Graham, Eileen K; Rutsohn, Joshua P; Turiano, Nicholas A et al. (2017) Personality Predicts Mortality Risk: An Integrative Data Analysis of 15 International Longitudinal Studies. J Res Pers 70:174-186
Clouston, Sean A P; Denier, Nicole (2017) Mental retirement and health selection: Analyses from the U.S. Health and Retirement Study. Soc Sci Med 178:78-86
Dodge, Hiroko H; Zhu, Jian; Woltjer, Randy et al. (2017) Risk of incident clinical diagnosis of Alzheimer's disease-type dementia attributable to pathology-confirmed vascular disease. Alzheimers Dement 13:613-623
Muniz-Terrera, Graciela; Robitaille, Annie; Kelly, Amanda et al. (2017) Latent growth models matched to research questions to answer questions about dynamics of change in multiple processes. J Clin Epidemiol 82:158-166
Clouston, Sean A P; Manganello, Jennifer A; Richards, Marcus (2017) A life course approach to health literacy: the role of gender, educational attainment and lifetime cognitive capability. Age Ageing 46:493-499

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