Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Chicago
United States
Zip Code
Gajewski, T F; Fallarino, F; Fields, P E et al. (2001) Absence of CTLA-4 lowers the activation threshold of primed CD8+ TCR-transgenic T cells: lack of correlation with Src homology domain 2-containing protein tyrosine phosphatase. J Immunol 166:3900-7
Szot, G L; Zhou, P; Rulifson, I et al. (2001) Different mechanisms of cardiac allograft rejection in wildtype and CD28-deficient mice. Am J Transplant 1:38-46
Alegre, M; Fallarino, F; Zhou, P et al. (2001) Transplantation and the CD28/CTLA4/B7 pathway. Transplant Proc 33:209-11
Zhou, P; Szot, G L; Guo, Z et al. (2000) Role of STAT4 and STAT6 signaling in allograft rejection and CTLA4-Ig-mediated tolerance. J Immunol 165:5580-7
Kulkarni, S; Holman, P O; Kopelan, A et al. (2000) Programmed cell death signaling via cell-surface expression of a single-chain antibody transgene. Transplantation 69:1209-17
Rezai, K A; Semnani, R T; Farrokh-Siar, L et al. (1999) Human fetal retinal pigment epithelial cells induce apoptosis in allogenic T-cells in a Fas ligand and PGE2 independent pathway. Curr Eye Res 18:430-9
van Seventer, G A; Semnani, R T; Palmer, E M et al. (1998) Integrins and T helper cell activation. Transplant Proc 30:4270-4
Smith, J A; Tang, Q; Bluestone, J A (1998) Partial TCR signals delivered by FcR-nonbinding anti-CD3 monoclonal antibodies differentially regulate individual Th subsets. J Immunol 160:4841-9
Fields, P E; Finch, R J; Gray, G S et al. (1998) B7.1 is a quantitatively stronger costimulus than B7.2 in the activation of naive CD8+ TCR-transgenic T cells. J Immunol 161:5268-75
Madrenas, J; Chau, L A; Smith, J et al. (1997) The efficiency of CD4 recruitment to ligand-engaged TCR controls the agonist/partial agonist properties of peptide-MHC molecule ligands. J Exp Med 185:219-29

Showing the most recent 10 out of 41 publications