Core - Statistics

Colton, Theodore

Abstract

The Statistics core will assist with study design and data analysis, particularly of sub-project 1 (Resolution of sexually acquired endometritis) but also of other projects. This core will determine sample sizes needed for adequate power; it will provide computerized data management services and final analysis in the cleanup phases of projects.

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Allergy and Infectious Diseases (NIAID)
• Type: Research Program Projects (P01)
• Project #: 5P01AI033087-03
• Application #: 3747346
• Support Year: 3
• Fiscal Year: 1994

Institution

• Name: Boston Medical Center
• DUNS #: 005492160
• City: Boston
• State: MA
• Country: United States
• Zip Code: 02118

Publications

Muhlecker, W; Gulati, S; McQuillen, D P et al. (1999) An essential saccharide binding domain for the mAb 2C7 established for Neisseria gonorrhoeae LOS by ES-MS and MSn. Glycobiology 9:157-71

McQuillen, D P; Gulati, S; Ram, S et al. (1999) Complement processing and immunoglobulin binding to Neisseria gonorrhoeae determined in vitro simulates in vivo effects. J Infect Dis 179:124-35

Qureshi, N; Kaltashov, I; Walker, K et al. (1997) Structure of the monophosphoryl lipid A moiety obtained from the lipopolysaccharide of Chlamydia trachomatis. J Biol Chem 272:10594-600

Lo, S K; Golenbock, D T; Sass, P M et al. (1997) Engagement of the Lewis X antigen (CD15) results in monocyte activation. Blood 89:307-14

Gulati, S; McQuillen, D P; Mandrell, R E et al. (1996) Immunogenicity of Neisseria gonorrhoeae lipooligosaccharide epitope 2C7, widely expressed in vivo with no immunochemical similarity to human glycosphingolipids. J Infect Dis 174:1223-37

Gulati, S; McQuillen, D P; Sharon, J et al. (1996) Experimental immunization with a monoclonal anti-idiotope antibody that mimics the Neisseria gonorrhoeae lipooligosaccharide epitope 2C7. J Infect Dis 174:1238-48

Ingalls, R R; Golenbock, D T (1995) CD11c/CD18, a transmembrane signaling receptor for lipopolysaccharide. J Exp Med 181:1473-9

Golenbock, D T; Bach, R R; Lichenstein, H et al. (1995) Soluble CD14 promotes LPS activation of CD14-deficient PNH monocytes and endothelial cells. J Lab Clin Med 125:662-71

Delude, R L; Savedra Jr, R; Zhao, H et al. (1995) CD14 enhances cellular responses to endotoxin without imparting ligand-specific recognition. Proc Natl Acad Sci U S A 92:9288-92

Ingalls, R R; Rice, P A; Qureshi, N et al. (1995) The inflammatory cytokine response to Chlamydia trachomatis infection is endotoxin mediated. Infect Immun 63:3125-30