Project Start
2000-09-01
Project End
2001-08-31
Budget Start
1997-10-01
Budget End
1998-09-30
Support Year
8
Fiscal Year
2000
Total Cost
$176,975
Indirect Cost
Name
University of Chicago
Department
Type
DUNS #
005421136
City
Chicago
State
IL
Country
United States
Zip Code
60637
Bour-Jordan, Hélène; Esensten, Jonathan H; Martinez-Llordella, Marc et al. (2011) Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/?B7 family. Immunol Rev 241:180-205
McClymont, Stephanie A; Putnam, Amy L; Lee, Michael R et al. (2011) Plasticity of human regulatory T cells in healthy subjects and patients with type 1 diabetes. J Immunol 186:3918-26
Bour-Jordan, Hélène; Bluestone, Jeffrey A (2009) Regulating the regulators: costimulatory signals control the homeostasis and function of regulatory T cells. Immunol Rev 229:41-66
Bluestone, Jeffrey A; Kuchroo, Vijay (2009) Autoimmunity. Curr Opin Immunol 21:579-81
Eagar, Todd N; Turley, Danielle M; Padilla, Josette et al. (2004) CTLA-4 regulates expansion and differentiation of Th1 cells following induction of peripheral T cell tolerance. J Immunol 172:7442-50
Eagar, Todd N; Karandikar, Nitin J; Bluestone, Jeffrey A et al. (2002) The role of CTLA-4 in induction and maintenance of peripheral T cell tolerance. Eur J Immunol 32:972-81
Bour-Jordan, Helene; Blueston, Jeffrey A (2002) CD28 function: a balance of costimulatory and regulatory signals. J Clin Immunol 22:1-7
Rulifson, Ingrid C; Szot, Gregory L; Palmer, Ed et al. (2002) Inability to induce tolerance through direct antigen presentation. Am J Transplant 2:510-9
Gajewski, T F; Fallarino, F; Fields, P E et al. (2001) Absence of CTLA-4 lowers the activation threshold of primed CD8+ TCR-transgenic T cells: lack of correlation with Src homology domain 2-containing protein tyrosine phosphatase. J Immunol 166:3900-7
O'Herrin, S M; Slansky, J E; Tang, Q et al. (2001) Antigen-specific blockade of T cells in vivo using dimeric MHC peptide. J Immunol 167:2555-60

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