Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program Projects (P01)
Project #
5P01AI035714-03
Application #
2071582
Study Section
Allergy & Clinical Immunology-1 (AITC)
Project Start
1994-08-01
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02215
Sayos, J; Wu, C; Morra, M et al. (2017) Pillars Article: The X-Linked Lymphoproliferative Disease Gene Product SAP Regulates Signals Induced through the Co-Receptor SLAM. Nature. 1998. 395: 462-469. J Immunol 199:1534-1541
Chaudhary, Anu; Leite, Mara; Kulasekara, Bridget R et al. (2016) Human Diversity in a Cell Surface Receptor that Inhibits Autophagy. Curr Biol 26:1791-801
Jabri, Bana; Terhorst, Cox (2014) Editorial overview: Autoimmunity. Curr Opin Immunol 31:v-vii
Sintes, Jordi; Cuenca, Marta; Romero, Xavier et al. (2013) Cutting edge: Ly9 (CD229), a SLAM family receptor, negatively regulates the development of thymic innate memory-like CD8+ T and invariant NKT cells. J Immunol 190:21-6
Detre, Cynthia; Keszei, Marton; Garrido-Mesa, Natividad et al. (2012) SAP expression in invariant NKT cells is required for cognate help to support B-cell responses. Blood 120:122-9
McDonald, Douglas R; Massaad, Michel J; Johnston, Alicia et al. (2010) Successful engraftment of donor marrow after allogeneic hematopoietic cell transplantation in autosomal-recessive hyper-IgE syndrome caused by dedicator of cytokinesis 8 deficiency. J Allergy Clin Immunol 126:1304-5.e3
McDonald, Douglas R; Goldman, Frederick; Gomez-Duarte, Oscar D et al. (2010) Impaired T-cell receptor activation in IL-1 receptor-associated kinase-4-deficient patients. J Allergy Clin Immunol 126:332-7, 337.e1-2
Detre, Cynthia; Keszei, Marton; Romero, Xavier et al. (2010) SLAM family receptors and the SLAM-associated protein (SAP) modulate T cell functions. Semin Immunopathol 32:157-71
Sintes, Jordi; Romero, Xavier; de Salort, Jose et al. (2010) Mouse CD84 is a pan-leukocyte cell-surface molecule that modulates LPS-induced cytokine secretion by macrophages. J Leukoc Biol 88:687-97
Diamond, Betty; Cunningham-Rundles, Charlotte; Fischer, Alain et al. (2010) Josiah F. Wedgwood (1950-2009). J Allergy Clin Immunol 125:506

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