Project Start
2002-09-01
Project End
2003-07-31
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
8
Fiscal Year
2002
Total Cost
$230,705
Indirect Cost
Name
Magee-Women's Hospital of Upmc
Department
Type
DUNS #
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Moncla, Bernard J; Guevara, Peter W; Wallace, James A et al. (2012) The inhibitory activity of typified propolis against Enterococcus species. Z Naturforsch C 67:249-56
Wang, Lin; Sassi, Alexandra Beumer; Patton, Dorothy et al. (2012) Development of a liposome microbicide formulation for vaginal delivery of octylglycerol for HIV prevention. Drug Dev Ind Pharm 38:995-1007
Moncla, B J; Pryke, K; Rohan, L C et al. (2012) Testing of viscous anti-HIV microbicides using Lactobacillus. J Microbiol Methods 88:292-6
Moncla, Bernard J; Pryke, Kara; Rohan, Lisa Cencia et al. (2011) Degradation of naturally occurring and engineered antimicrobial peptides by proteases. Adv Biosci Biotechnol 2:404-408
Skinner, M C; Stamm, W E; Lampe, M L (2009) Chlamydia trachomatis laboratory strains versus recent clinical isolates: implications for routine microbicide testing. Antimicrob Agents Chemother 53:1482-9
Patton, Dorothy L; Sweeney, Yvonne T Cosgrove; Paul, Kathleen J (2009) A summary of preclinical topical microbicide rectal safety and efficacy evaluations in a pigtailed macaque model. Sex Transm Dis 36:350-6
Sassi, Alexandra B; Isaacs, Charles E; Moncla, Bernard J et al. (2008) Effects of physiological fluids on physical-chemical characteristics and activity of topical vaginal microbicide products. J Pharm Sci 97:3123-39
Moncla, B J; Pryke, K; Isaacs, Charles E (2008) Killing of Neisseria gonorrhoeae, Streptococcus agalactiae (group B streptococcus), Haemophilus ducreyi, and vaginal Lactobacillus by 3-O-octyl-sn-glycerol. Antimicrob Agents Chemother 52:1577-9
Deslouches, Berthony; Gonzalez, Ivan A; DeAlmeida, Dilhari et al. (2007) De novo-derived cationic antimicrobial peptide activity in a murine model of Pseudomonas aeruginosa bacteraemia. J Antimicrob Chemother 60:669-72
Patton, D L; Cosgrove Sweeney, Y T; McCarthy, T D et al. (2006) Preclinical safety and efficacy assessments of dendrimer-based (SPL7013) microbicide gel formulations in a nonhuman primate model. Antimicrob Agents Chemother 50:1696-700

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