The Administrative core will be housed within the Center for Immunology at the University of Texas Southwestern Medical Center at Dallas (UTSW). This core will function to administer the funds, coordinate the interactions of personnel within the various Projects and Cores, and provide administrative assistance. The activities of this core will support all three Projects and the Core facilities of this Program Project Grant (PPG) equivalently. We have three specific aims.
The first aim will be to provide leadership for the program project. Dr. Wakeland will provide overall leadership for the PPG, and Dr. Mohan will serve as Associate Director. Their role will be to participate in and coordinate bi-weekly work in progress meetings of all PPG personnel and to oversee and coordinate annual reports. The second specific aim will be to administer the program project. Ms. Marie Warwick will direct the fiscal administration of the PPG and will oversee the distribution of funds to the projects and Cores. She will interface with UT Southwestern and NIH administrative personnel to assure compliance with all issues relevant to the administration of grant funds. Additional administrative assistance will be provided by Ms. Bedford, who will assist PPG personnel with the preparation of manuscripts, progress reports, travel arrangements, and scientific presentations. The third specific aim will be to organize and conduct the annual meetings of the Scientific Advisory Board with PPG personnel. These meetings will involve scientific presentations to the SAB by all key personnel in the PPG.
|Luo, Wei; Mayeux, Jessica; Gutierrez, Toni et al. (2014) A balance between B cell receptor and inhibitory receptor signaling controls plasma cell differentiation by maintaining optimal Ets1 levels. J Immunol 193:909-920|
|Cuda, Carla M; Misharin, Alexander V; Gierut, Angelica K et al. (2014) Caspase-8 acts as a molecular rheostat to limit RIPK1- and MyD88-mediated dendritic cell activation. J Immunol 192:5548-60|
|Dozmorov, Igor; Dominguez, Nicolas; Sestak, Andrea L et al. (2013) Evidence of dynamically dysregulated gene expression pathways in hyperresponsive B cells from African American lupus patients. PLoS One 8:e71397|
|Gutierrez, Toni; Mayeux, Jessica M; Ortega, Sterling B et al. (2013) IL-21 promotes the production of anti-DNA IgG but is dispensable for kidney damage in lyn-/- mice. Eur J Immunol 43:382-93|
|Cuda, Carla M; Agrawal, Hemant; Misharin, Alexander V et al. (2012) Requirement of myeloid cell-specific Fas expression for prevention of systemic autoimmunity in mice. Arthritis Rheum 64:808-20|
|Gutierrez, Toni; Halcomb, Kristina E; Coughran, Alanna J et al. (2010) Separate checkpoints regulate splenic plasma cell accumulation and IgG autoantibody production in Lyn-deficient mice. Eur J Immunol 40:1897-905|
|Wang, Andrew; Guilpain, Philippe; Chong, Benjamin F et al. (2010) Dysregulated expression of CXCR4/CXCL12 in subsets of patients with systemic lupus erythematosus. Arthritis Rheum 62:3436-46|
|Jacob, Chaim O; Zhu, Jiankun; Armstrong, Don L et al. (2009) Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus. Proc Natl Acad Sci U S A 106:6256-61|
|Wang, Andrew; Fairhurst, Anna-Marie; Tus, Katalin et al. (2009) CXCR4/CXCL12 hyperexpression plays a pivotal role in the pathogenesis of lupus. J Immunol 182:4448-58|
|Fairhurst, Anna-Marie; Mathian, Alexis; Connolly, John E et al. (2008) Systemic IFN-alpha drives kidney nephritis in B6.Sle123 mice. Eur J Immunol 38:1948-60|
Showing the most recent 10 out of 30 publications