The Adminstrative Core has both scientific and administrative responsibilities and its activities are directed towards a two-fold goal: to provide the Program with a mechanism for timely and accurate communications between the institutional administrative bodies where work is performed {i.e. University of lowa and Buck Institute) and the NIH. and to meet and coordinate the administrative needs of individual projects within the program. All administrative functions will be coordinated through the Administrative Core which will therefore serve each of the specific projects. Scientific responsibilities include the fostering of coordination of project integration, organization of biweekly work-in-progress Inflammation Program sessions, consultation with the Executive Committee and the extramural Advisory Committee, and preparation of scientific reports relating progress of research. Administrative responsibilities include allocation of budgets in accordance with NIH guidelines, careful justifications of expenditures, allocation of travel funds among investigators in an equitable manner, preparing annual budgets and projections, and aiding investigators in issues related to personnel. Taken as a whole, the overall role of this core will be to facilitate the proposed research strategies in order to maximize the productivity of each project and of the program as a whole.

Public Health Relevance

The fundamental mission of the Administrative Core is to oversee the coordination of all three projects and the analytical core into an integrated, cohesive working unit that functions more creatively and productively than would the sum of activities of each component individually.

National Institute of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Research Program Projects (P01)
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Special Emphasis Panel (ZAI1-LG-I (J1))
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University of Iowa
Iowa City
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Stevenson, Taylor C; Cywes-Bentley, Colette; Moeller, Tyler D et al. (2018) Immunization with outer membrane vesicles displaying conserved surface polysaccharide antigen elicits broadly antimicrobial antibodies. Proc Natl Acad Sci U S A 115:E3106-E3115
Greenlee-Wacker, Mallary C; Nauseef, William M (2017) IFN-? targets macrophage-mediated immune responses toward Staphylococcus aureus. J Leukoc Biol 101:751-758
Grishkovskaya, Irina; Paumann-Page, Martina; Tscheliessnig, Rupert et al. (2017) Structure of human promyeloperoxidase (proMPO) and the role of the propeptide in processing and maturation. J Biol Chem 292:8244-8261
Post, Deborah M B; Slütter, Bram; Schilling, Birgit et al. (2017) Characterization of Inner and Outer Membrane Proteins from Francisella tularensis Strains LVS and Schu S4 and Identification of Potential Subunit Vaccine Candidates. MBio 8:
Wacker, Mark A; Teghanemt, Athmane; Weiss, Jerrold P et al. (2017) High-affinity caspase-4 binding to LPS presented as high molecular mass aggregates or in outer membrane vesicles. Innate Immun 23:336-344
Greenlee-Wacker, Mallary C; Kremserová, Silvie; Nauseef, William M (2017) Lysis of human neutrophils by community-associated methicillin-resistant Staphylococcus aureus. Blood 129:3237-3244
Greenlee-Wacker, Mallary C (2016) Clearance of apoptotic neutrophils and resolution of inflammation. Immunol Rev 273:357-70
Nauseef, William M (2016) Neutrophils, from cradle to grave and beyond. Immunol Rev 273:5-10
Kinkead, Lauren C; Allen, Lee-Ann H (2016) Multifaceted effects of Francisella tularensis on human neutrophil function and lifespan. Immunol Rev 273:266-81
Nauseef, William M; Kubes, Paul (2016) Pondering neutrophil extracellular traps with healthy skepticism. Cell Microbiol 18:1349-57

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