Abstract

The administrative core at The University of Chicago will provide the projects comprising the program consortium on-going administrative support. It will also provide travel support for the annual meetings of the project leaders and key personnel plus travel support for the program's annual meeting invited speaker/external advisor.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program Projects (P01)
Project #
5P01AI053725-10
Application #
8376762
Study Section
Special Emphasis Panel (ZAI1-CL-I)
Project Start
Project End
2014-03-31
Budget Start
2012-04-01
Budget End
2013-03-31
Support Year
10
Fiscal Year
2012
Total Cost
$24,247
Indirect Cost
$727

  Institution

Name
University of Chicago
Department
Type
DUNS #
005421136
City
Chicago
State
IL
Country
United States
Zip Code
60637

  Publications

Deng, S; Bai, L; Reboulet, R et al. (2014) A peptide-free, liposome-based oligosaccharide vaccine, adjuvanted with a natural killer T cell antigen, generates robust antibody responses in vivo. Chem Sci 5:1437-1441
Kain, Lisa; Webb, Bill; Anderson, Brian L et al. (2014) The identification of the endogenous ligands of natural killer T cells reveals the presence of mammalian ?-linked glycosylceramides. Immunity 41:543-54
Tefit, Josianne Nitcheu; Crabé, Sandrine; Orlandini, Bernard et al. (2014) Efficacy of ABX196, a new NKT agonist, in prophylactic human vaccination. Vaccine 32:6138-45
Freigang, Stefan; Kain, Lisa; Teyton, Luc (2013) Transport and uptake of immunogenic lipids. Mol Immunol 55:179-81
Bai, Li; Deng, Shenglou; Reboulet, Rachel et al. (2013) Natural killer T (NKT)-B-cell interactions promote prolonged antibody responses and long-term memory to pneumococcal capsular polysaccharides. Proc Natl Acad Sci U S A 110:16097-102
Anderson, Brian L; Teyton, Luc; Bendelac, Albert et al. (2013) Stimulation of natural killer T cells by glycolipids. Molecules 18:15662-88
Luoma, Adrienne M; Castro, Caitlin D; Mayassi, Toufic et al. (2013) Crystal structure of V?1 T cell receptor in complex with CD1d-sulfatide shows MHC-like recognition of a self-lipid by human ?? T cells. Immunity 39:1032-42
Constantinides, Michael G; Bendelac, Albert (2013) Transcriptional regulation of the NKT cell lineage. Curr Opin Immunol 25:161-7
Bai, Li; Constantinides, Michael G; Thomas, Seddon Y et al. (2012) Distinct APCs explain the cytokine bias of ?-galactosylceramide variants in vivo. J Immunol 188:3053-61
Seiler, Michael P; Mathew, Rebecca; Liszewski, Megan K et al. (2012) Elevated and sustained expression of the transcription factors Egr1 and Egr2 controls NKT lineage differentiation in response to TCR signaling. Nat Immunol 13:264-71

Showing the most recent 10 out of 33 publications