Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program Projects (P01)
Project #
7P01AI060896-03
Application #
7220651
Study Section
Special Emphasis Panel (ZAI1)
Project Start
Project End
Budget Start
2006-05-01
Budget End
2007-04-30
Support Year
3
Fiscal Year
2005
Total Cost
$179,260
Indirect Cost
Name
Feinstein Institute for Medical Research
Department
Type
DUNS #
110565913
City
Manhasset
State
NY
Country
United States
Zip Code
11030
Zhong, Xuemei; Rothstein, Thomas L (2011) L2pB1: a new player in autoimmunity. Mol Immunol 48:1292-300
Kaku, H; Rothstein, T L (2010) Octamer binding protein 2 (Oct2) regulates PD-L2 gene expression in B-1 cells through lineage-specific activity of a unique, intronic promoter. Genes Immun 11:55-66
Holodick, Nichol E; Tumang, Joseph R; Rothstein, Thomas L (2010) Immunoglobulin secretion by B1 cells: differential intensity and IRF4-dependence of spontaneous IgM secretion by peritoneal and splenic B1 cells. Eur J Immunol 40:3007-16
Gumina, Maria R; Xu, Chenjia; Chiles, Thomas C (2010) Cyclin D3 is dispensable for human diffuse large B-cell lymphoma survival and growth: evidence for redundancy with cyclin E. Cell Cycle 9:820-8
Holodick, Nichol E; Tumang, Joseph R; Rothstein, Thomas L (2009) Continual signaling is responsible for constitutive ERK phosphorylation in B-1a cells. Mol Immunol 46:3029-36
Repetny, Karen J; Zhong, Xuemei; Holodick, Nichol E et al. (2009) Binding of LBP-1a to specific immunoglobulin switch regions in vivo correlates with specific repression of class switch recombination. Eur J Immunol 39:1387-94
Zhong, Xuemei; Lau, Stanley; Bai, Chunyan et al. (2009) A novel subpopulation of B-1 cells is enriched with autoreactivity in normal and lupus-prone mice. Arthritis Rheum 60:3734-43
Holodick, Nichol E; Repetny, Karen; Zhong, Xuemei et al. (2009) Adult BM generates CD5+ B1 cells containing abundant N-region additions. Eur J Immunol 39:2383-94
Dufort, Fay J; Bleiman, Blair F; Gumina, Maria R et al. (2007) Cutting edge: IL-4-mediated protection of primary B lymphocytes from apoptosis via Stat6-dependent regulation of glycolytic metabolism. J Immunol 179:4953-7
Nikolajczyk, Barbara S; Sardi, Sylvia H; Tumang, Joseph R et al. (2007) Immunoglobulin kappa enhancers are differentially regulated at the level of chromatin structure. Mol Immunol 44:3407-15

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