Abstract

The Administrative Core will provide comprehensive administrative support for all Projects/Cores, as wellas to fulfill reporting requirements to DAIDS and provide ongoing assessment of the programs progress.Specific areas of responsibility will include: 1. Provision of biostatistical support; 2. supportive datamanagement, information exchange; 3. coordination of communication among program investigators; 5.addressing intellectual property issues; 6. support of the external scientific advisory board; and 7. travelcoordination and support.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program Projects (P01)
Project #
1P01AI071306-01A1
Application #
7294524
Study Section
Special Emphasis Panel (ZAI1-MPM-A (J1))
Project Start
2007-01-01
Project End
2012-03-31
Budget Start
2007-04-15
Budget End
2008-03-31
Support Year
1
Fiscal Year
2007
Total Cost
$328,501
Indirect Cost

  Institution

Name
Harvard University
Department
Type
DUNS #
047006379
City
Boston
State
MA
Country
United States
Zip Code
02115

  Publications

Shang, L; Smith, A J; Reilly, C S et al. (2018) Vaccine-modified NF-kB and GR signaling in cervicovaginal epithelium correlates with protection. Mucosal Immunol 11:512-522
Shang, L; Duan, L; Perkey, K E et al. (2017) Epithelium-innate immune cell axis in mucosal responses to SIV. Mucosal Immunol 10:508-519
Zeng, Ming; Smith, Anthony J; Shang, Liang et al. (2016) Mucosal Humoral Immune Response to SIVmac239?nef Vaccination and Vaginal Challenge. J Immunol 196:2809-18
Adnan, Sama; Colantonio, Arnaud D; Yu, Yi et al. (2015) CD8 T cell response maturation defined by anentropic specificity and repertoire depth correlates with SIV?nef-induced protection. PLoS Pathog 11:e1004633
Shang, Liang; Smith, Anthony J; Duan, Lijie et al. (2014) NK cell responses to simian immunodeficiency virus vaginal exposure in naive and vaccinated rhesus macaques. J Immunol 193:277-84
George, Michael D; Hu, William; Billingsley, James M et al. (2014) Transcriptional profiling of peripheral CD8+T cell responses to SIV?nef and SIVmac251 challenge reveals a link between protective immunity and induction of systemic immunoregulatory mechanisms. Virology 468-470:581-91
Li, Qingsheng; Zeng, Ming; Duan, Lijie et al. (2014) Live simian immunodeficiency virus vaccine correlate of protection: local antibody production and concentration on the path of virus entry. J Immunol 193:3113-25
Smith, Anthony J; Wietgrefe, Stephen W; Shang, Liang et al. (2014) Live simian immunodeficiency virus vaccine correlate of protection: immune complex-inhibitory Fc receptor interactions that reduce target cell availability. J Immunol 193:3126-33
Manrique, Julieta; Piatak, Michael; Lauer, William et al. (2013) Influence of mismatch of Env sequences on vaccine protection by live attenuated simian immunodeficiency virus. J Virol 87:7246-54
Rahmberg, Andrew R; Neidermyer Jr, William J; Breed, Matthew W et al. (2013) Tetherin upregulation in simian immunodeficiency virus-infected macaques. J Virol 87:13917-21

Showing the most recent 10 out of 31 publications