The Administrative Core consists of two major functional units - the Executive Unit and the DataManagement, Statistics, and Information Technology (DMS/IT) Unit.
The Aims of the Executive Unit areto 1) provide overall scientific and programmatic leadership and direction, 2) oversee and coordinate theactivities of Projects 1 and 2, 3) ensure reliable exchange of information and collaboration among all theunits and investigators, 4) coordinate and oversee management of the Program Project's fiscal resources,and 5) promote and ensure the Program Project's adherence to relevant federal, University, and IRBrequirements.
The Aims of the Data Management, Statistics, and Information Technology (DMS/IT) Unit areto 6) provide a state-of-the-art data management system and methods capable of supporting the interactiveprojects of multiple participating investigators, 7) provide a set of online resources and communicationstechnologies that facilitate scholarly exchange, distance-independent collaboration, informationdissemination and project-specific training, and 8) provide statistical expertise in design, modeling, dataanalysis, statistical writing, and the development of novel methodologies as related to the execution ofProjects 1 and 2.Related to the specific aims of Project 1 and 2, the Clinical and Specimen Core will recruit a substantialnumber of study participants, each of whom will contribute clinical specimens for laboratory evaluation.Project 1 will generate epidemiological and behavioral data on the participants, while Project 2 will generatelaboratory data using the clinical specimens. The Administrative Core will play a central role in coordinatingthe administrative, fiscal and personnel support required to achieve the scientific mission of thesecomponents and fostering the synergistic interaction among them. The Administrative Core will also becritical in managing the extensive amount of data from these projects and conducting the sophisticatedanalyses necessary to provide robust and valid conclusions.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program Projects (P01)
Project #
1P01AI074621-01A1
Application #
7468160
Study Section
Special Emphasis Panel (ZAI1-MH-A (S1))
Project Start
2008-03-15
Project End
2013-02-28
Budget Start
2008-03-15
Budget End
2009-02-28
Support Year
1
Fiscal Year
2008
Total Cost
$894,778
Indirect Cost
Name
University of California San Diego
Department
Type
DUNS #
804355790
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Chaillon, Antoine; Gianella, Sara; Lada, Steven M et al. (2018) Size, Composition, and Evolution of HIV DNA Populations during Early Antiretroviral Therapy and Intensification with Maraviroc. J Virol 92:
Grebe, Eduard; Welte, Alex; Hall, Jake et al. (2017) Infection Staging and Incidence Surveillance Applications of High Dynamic Range Diagnostic Immuno-Assay Platforms. J Acquir Immune Defic Syndr 76:547-555
Morris, Sheldon R; Zhao, Mitchell; Smith, Davey M et al. (2017) Longitudinal Viral Dynamics in Semen During Early HIV Infection. Clin Infect Dis 64:428-434
Osorio, Georgina; Hoenigl, Martin; Quartarolo, Jennifer et al. (2017) Evaluation of opt-out inpatient HIV screening at an urban teaching hospital. AIDS Care 29:1014-1018
Pines, Heather A; Karris, Maile Y; Little, Susan J (2017) Sexual Partner Concurrency Among Partners Reported by MSM with Recent HIV Infection. AIDS Behav 21:3026-3034
Gianella, Sara; Chaillon, Antoine; Mutlu, Ece A et al. (2017) Effect of cytomegalovirus and Epstein-Barr virus replication on intestinal mucosal gene expression and microbiome composition of HIV-infected and uninfected individuals. AIDS 31:2059-2067
Hoenigl, Martin; Braun, Dominique L; Kouyos, Roger et al. (2017) Evaluation of the Predictive Potential of the Short Acute Retroviral Syndrome Severity Score for HIV-1 Disease Progression in Individuals With Acute HIV Infection. J Acquir Immune Defic Syndr 74:e114-e117
Graves, Susannah K; Little, Susan J; Hoenigl, Martin (2017) Risk profile and HIV testing outcomes of women undergoing community-based testing in San Diego 2008-2014. Sci Rep 7:42183
Green, Nella; Hoenigl, Martin; Chaillon, Antoine et al. (2017) Partner services in adults with acute and early HIV infection. AIDS 31:287-293
Gianella, Sara; Taylor, Jeff; Brown, Timothy R et al. (2017) Can research at the end of life be a useful tool to advance HIV cure? AIDS 31:1-4

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