The Administrative Core (Core C) will provide organizational and administrative support to facilitate communications, reporting, budget management, and other tasks that interface with the two projects and two scientific cores. The administrative core will include Dr. Pamela J. Bjorkman as Core Leader, her Administrative Assistant, a Research Scientist in her lab, the Lab Administrator in Dr. Michel Nussenzweig's lab, and the Administrative Assistant for Dr. Jost Vielmetter, the Core A and Core B Leader. The Administrative Core will 1) Organize and govern the HIVRAD project and 2) Coordinate the interactions within the HIVRAD project and with the broader scientific community. This includes arranging formal communications among investigators, preparing protocol submissions and annual renewals to the Institutional Review Boards, coordinating material transfer agreements, preparing reports and manuscripts, monitoring budgets, planning annual meetings and monthly conference calls, maintaining the HIVRAD website, and generally overseeing the scientific and administrative needs of the Program Project. In addition, the Administrative Core staff will assist in the effective sharing of data by maintaining shared cloud-based notebooks and databases.
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| Stadtmueller, Beth M; Bridges, Michael D; Dam, Kim-Marie et al. (2018) DEER Spectroscopy Measurements Reveal Multiple Conformations of HIV-1 SOSIP Envelopes that Show Similarities with Envelopes on Native Virions. Immunity 49:235-246.e4 |
| Gautam, Rajeev; Nishimura, Yoshiaki; Gaughan, Natalie et al. (2018) A single injection of crystallizable fragment domain-modified antibodies elicits durable protection from SHIV infection. Nat Med 24:610-616 |
| Cohn, Lillian B; da Silva, Israel T; Valieris, Renan et al. (2018) Clonal CD4+ T cells in the HIV-1 latent reservoir display a distinct gene profile upon reactivation. Nat Med 24:604-609 |
| Horwitz, Joshua A; Bar-On, Yotam; Lu, Ching-Lan et al. (2017) Non-neutralizing Antibodies Alter the Course of HIV-1 Infection In Vivo. Cell 170:637-648.e10 |
| Nishimura, Yoshiaki; Gautam, Rajeev; Chun, Tae-Wook et al. (2017) Early antibody therapy can induce long-lasting immunity to SHIV. Nature 543:559-563 |
| Bournazos, Stylianos; Ravetch, Jeffrey V (2017) Anti-retroviral antibody Fc?R-mediated effector functions. Immunol Rev 275:285-295 |
| Gristick, Harry B; Wang, Haoqing; Bjorkman, Pamela J (2017) X-ray and EM structures of a natively glycosylated HIV-1 envelope trimer. Acta Crystallogr D Struct Biol 73:822-828 |
| Bournazos, Stylianos; Wang, Taia T; Dahan, Rony et al. (2017) Signaling by Antibodies: Recent Progress. Annu Rev Immunol 35:285-311 |
| Bournazos, Stylianos; Ravetch, Jeffrey V (2017) Fc? Receptor Function and the Design of Vaccination Strategies. Immunity 47:224-233 |
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