Administrative Core The HIVRAD Administrative Core will coordinate and provide oversight for this HIVRAD Program Project grant. The Administrative Core will both maintain scientific and managerial oversight over the Projects and Cores and ensure that the HIVRAD activities synergize with other AIDS vaccine-related activities at Duke and nationally. In addition, the Administrative Core will ensure that the scientific Projects and Cores make steady progress toward meeting project milestones, with appropriate statistical oversight. Other specific responsibilities of the Administrative Core include the following: planning meetings with Scientific Advisory Board, making travel arrangements to offsite NIAID-sponsored meetings and programs, managing funds, planning the agenda for internal scientific meetings, ensuring statistical oversight and managing the statistical team, preparing periodic research reports and related manuscripts, and ensuring compliance with all institutional and federal guidelines. In sum, the Administrative Core will help ensure successful collaboration and the overall success of this unified research effort.

Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Research Program Projects (P01)
Project #
5P01AI117915-04
Application #
9655132
Study Section
Special Emphasis Panel (ZAI1)
Program Officer
Singh, Anjali
Project Start
Project End
Budget Start
2018-04-01
Budget End
2019-03-31
Support Year
4
Fiscal Year
2018
Total Cost
Indirect Cost
Name
Duke University
Department
Type
DUNS #
044387793
City
Durham
State
NC
Country
United States
Zip Code
27705
Himes, Jonathon E; Goswami, Ria; Mangan, Riley J et al. (2018) Polyclonal HIV envelope-specific breast milk antibodies limit founder SHIV acquisition and cell-associated virus loads in infant rhesus monkeys. Mucosal Immunol 11:1716-1726
Dennis, Maria; Eudailey, Joshua; Pollara, Justin et al. (2018) Co-administration of CH31 broadly neutralizing antibody does not affect development of vaccine-induced anti-HIV-1 envelope antibody responses in infant Rhesus macaques. J Virol :
Eudailey, Joshua A; Dennis, Maria L; Parker, Morgan E et al. (2018) Maternal HIV-1 Env Vaccination for Systemic and Breast Milk Immunity To Prevent Oral SHIV Acquisition in Infant Macaques. mSphere 3:
Martinez, David R; Fouda, Genevieve G; Peng, Xinxia et al. (2018) Noncanonical placental Fc receptors: What is their role in modulating transplacental transfer of maternal IgG? PLoS Pathog 14:e1007161
Phillips, Bonnie; Van Rompay, Koen K A; Rodriguez-Nieves, Jennifer et al. (2018) Adjuvant-Dependent Enhancement of HIV Env-Specific Antibody Responses in Infant Rhesus Macaques. J Virol 92:
Phillips, Bonnie; Fouda, Genevieve G; Eudailey, Josh et al. (2017) Impact of Poxvirus Vector Priming, Protein Coadministration, and Vaccine Intervals on HIV gp120 Vaccine-Elicited Antibody Magnitude and Function in Infant Macaques. Clin Vaccine Immunol 24:
Zhang, Ruijun; Martinez, David R; Nguyen, Quang N et al. (2016) Envelope-specific B-cell populations in African green monkeys chronically infected with simian immunodeficiency virus. Nat Commun 7:12131
Nelson, Cody S; Pollara, Justin; Kunz, Erika L et al. (2016) Combined HIV-1 Envelope Systemic and Mucosal Immunization of Lactating Rhesus Monkeys Induces a Robust Immunoglobulin A Isotype B Cell Response in Breast Milk. J Virol 90:4951-4965
Nguyen, Quang N; Himes, Jonathon E; Martinez, David R et al. (2016) The Impact of the Gut Microbiota on Humoral Immunity to Pathogens and Vaccination in Early Infancy. PLoS Pathog 12:e1005997
Kelly, Matthew S; Benjamin, Daniel K; Puopolo, Karen M et al. (2015) Postnatal Cytomegalovirus Infection and the Risk for Bronchopulmonary Dysplasia. JAMA Pediatr 169:e153785

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