The main focus of the Administrative Core is to integrate and coordinate the functioning of the 4 projects and the Analytical Core, aimed at pursuing CAM research on Botanicals, Epigenetics and Inflammation by enhancing the interactive environment at the Center. This Core will coordinate the research mission of the Center, establish timeline for achieving research milestones and monitor success, interact with advisory groups, work with USC leadership to secure support, and enhance the visibility of CAM research nationally and internationally. In addition, the Administrative Core will provide oversight into the day to day operations of the Center. Specifically, this Core will monitor the financial and personnel issues of all the projects and cores. It will be responsible for organizing the scientific activities of the investigators at the Center. Yet another role of the Core will be in coordinating the functions of the support groups which include the Steering Committee, the Internal Advisory Committee and the External Advisory Committee. These Committees will provide input to the Program Director in setting priorities, allocation of resources, assessment of research progress, and implementation of any remedial action, if necessary. The Core will promote interdisciplinary research by maintaining communication with the other colleges including USC School of Medicine at Greenville, Pharmacy, Public Health, Nursing, Social Work, and Engineering. The Administrative Core, during the past funding cycle, was responsible for securing significant institutional support which led to the award of NIH COBRE grant to help recruit and train 16 new junior tenure-track faculty in CAM research. The Core will continue such efforts to further enhance CAM research at USC. The Core will serve as a liaison with the NCCAM as well as with the regulatory agencies so as to ensure compliance with policy issues. The Core will foster development of new pilot projects that will initiate new faculty or established investigators to pursue research on CAM. The Core will also promote communications with clinicians so as to develop translational research. The Core will encourage technology transfer of the products that may develop from these projects. The Core will assist in recruitment of faculty, technologists, postdoctoral and predoctoral trainees. The PI is already involved in enhancing the recruitment of underrepresented minority students and faculty with significant success. The Core will continue to pursue such efforts. In summary, the core will play a central role in ensuring integration of the various projects of the Center resulting in highly effective and productive management of the Center.

Agency
National Institute of Health (NIH)
Institute
National Center for Complementary & Alternative Medicine (NCCAM)
Type
Research Program Projects (P01)
Project #
5P01AT003961-07
Application #
8927533
Study Section
Special Emphasis Panel (ZAT1)
Project Start
Project End
Budget Start
2015-09-01
Budget End
2016-08-31
Support Year
7
Fiscal Year
2015
Total Cost
Indirect Cost
Name
University of South Carolina at Columbia
Department
Type
DUNS #
041387846
City
Columbia
State
SC
Country
United States
Zip Code
29208
Bam, Marpe; Yang, Xiaoming; Sen, Souvik et al. (2018) Characterization of Dysregulated miRNA in Peripheral Blood Mononuclear Cells from Ischemic Stroke Patients. Mol Neurobiol 55:1419-1429
Elliott, David M; Singh, Narendra; Nagarkatti, Mitzi et al. (2018) Cannabidiol Attenuates Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis Through Induction of Myeloid-Derived Suppressor Cells. Front Immunol 9:1782
Kenne, Gabriel J; Gummadidala, Phani M; Omebeyinje, Mayomi H et al. (2018) Activation of Aflatoxin Biosynthesis Alleviates Total ROS in Aspergillus parasiticus. Toxins (Basel) 10:
Bader, Jackie E; Enos, Reilly T; Velázquez, Kandy T et al. (2018) Macrophage depletion using clodronate liposomes decreases tumorigenesis and alters gut microbiota in the AOM/DSS mouse model of colon cancer. Am J Physiol Gastrointest Liver Physiol 314:G22-G31
Wirth, Michael D; Sevoyan, Maria; Hofseth, Lorne et al. (2018) The Dietary Inflammatory Index is associated with elevated white blood cell counts in the National Health and Nutrition Examination Survey. Brain Behav Immun 69:296-303
Becker, William; Nagarkatti, Mitzi; Nagarkatti, Prakash S (2018) miR-466a Targeting of TGF-?2 Contributes to FoxP3+ Regulatory T Cell Differentiation in a Murine Model of Allogeneic Transplantation. Front Immunol 9:688
Dopkins, Nicholas; Nagarkatti, Prakash S; Nagarkatti, Mitzi (2018) The role of gut microbiome and associated metabolome in the regulation of neuroinflammation in multiple sclerosis and its implications in attenuating chronic inflammation in other inflammatory and autoimmune disorders. Immunology 154:178-185
Abron, Jessica D; Singh, Narendra P; Mishra, Manoj K et al. (2018) An endogenous aryl hydrocarbon receptor ligand, ITE, induces regulatory T cells and ameliorates experimental colitis. Am J Physiol Gastrointest Liver Physiol 315:G220-G230
Alghetaa, Hasan; Mohammed, Amira; Sultan, Muthanna et al. (2018) Resveratrol protects mice against SEB-induced acute lung injury and mortality by miR-193a modulation that targets TGF-? signalling. J Cell Mol Med 22:2644-2655
Zhang, Tao; Zhou, Juhua; Man, Gene Chi Wai et al. (2018) MDSCs drive the process of endometriosis by enhancing angiogenesis and are a new potential therapeutic target. Eur J Immunol 48:1059-1073

Showing the most recent 10 out of 178 publications