This proposal requests continuing support for an Epidemiology and Biostatistics Research Program as a major component of the Los Angeles County/University of Southern California Cancer Center. A large part of the research effort is the Cancer Surveillance Program (CSP) headed by Dr. Thomas Mack. The CSP provides prompt reporting and detailed demographic data on virtually all new cancer cases diagnosed in the entire population of seven million residents of Los Angeles County. A major function of the CSP is to provide cancer patient identification for etiologic field studies. The descriptive information from the CSP provides additional etiological clues and a system for checking the consistency of suggested causal associations with cancer rates in the population. The CSP also identifies high risk program targets, and constitutes a cancer research organization with a presence in each of the county's diagnostic facilities. The Biostatistics Unit headed by Dr. Malcolm Pike supports some field staff as well as the analytic component of our field studies. Development of new statistical methods to deal with these field studies and other cancer related studies is also undertaken by this unit. Funds for most field studies are currently being obtained from several research contracts and grants. The desirability of having the capability of making a rapid and flexible response to newly suggested hypotheses demands some field staff without unalterable commitments.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA017054-11
Application #
3092734
Study Section
(SRC)
Project Start
1979-04-01
Project End
1987-03-31
Budget Start
1986-04-01
Budget End
1987-03-31
Support Year
11
Fiscal Year
1986
Total Cost
Indirect Cost
Name
University of Southern California
Department
Type
Schools of Medicine
DUNS #
041544081
City
Los Angeles
State
CA
Country
United States
Zip Code
90033
Ma, Huiyan; Ursin, Giske; Xu, Xinxin et al. (2018) Body mass index at age 18 years and recent body mass index in relation to risk of breast cancer overall and ER/PR/HER2-defined subtypes in white women and African-American women: a pooled analysis. Breast Cancer Res 20:5
Liu, Gang; Mukherjee, Bhramar; Lee, Seunggeun et al. (2018) Robust Tests for Additive Gene-Environment Interaction in Case-Control Studies Using Gene-Environment Independence. Am J Epidemiol 187:366-377
Ong, Jue-Sheng; Hwang, Liang-Dar; Cuellar-Partida, Gabriel et al. (2018) Assessment of moderate coffee consumption and risk of epithelial ovarian cancer: a Mendelian randomization study. Int J Epidemiol 47:450-459
Harris, Holly R; Babic, Ana; Webb, Penelope M et al. (2018) Polycystic Ovary Syndrome, Oligomenorrhea, and Risk of Ovarian Cancer Histotypes: Evidence from the Ovarian Cancer Association Consortium. Cancer Epidemiol Biomarkers Prev 27:174-182
Lu, Yingchang; Beeghly-Fadiel, Alicia; Wu, Lang et al. (2018) A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk. Cancer Res 78:5419-5430
Peres, Lauren C; Risch, Harvey; Terry, Kathryn L et al. (2018) Racial/ethnic differences in the epidemiology of ovarian cancer: a pooled analysis of 12 case-control studies. Int J Epidemiol 47:460-472
Lee, Eunjung; Luo, Jianning; Schumacher, Fredrick R et al. (2018) Growth factor genes and change in mammographic density after stopping combined hormone therapy in the California Teachers Study. BMC Cancer 18:1072
Zhong, Charlie; Cockburn, Myles; Cozen, Wendy et al. (2017) Evaluating the use of friend or family controls in epidemiologic case-control studies. Cancer Epidemiol 46:9-13
Praestegaard, Camilla; Jensen, Allan; Jensen, Signe M et al. (2017) Cigarette smoking is associated with adverse survival among women with ovarian cancer: Results from a pooled analysis of 19 studies. Int J Cancer 140:2422-2435
Reid, Brett M; Permuth, Jennifer B; Chen, Y Ann et al. (2017) Integration of Population-Level Genotype Data with Functional Annotation Reveals Over-Representation of Long Noncoding RNAs at Ovarian Cancer Susceptibility Loci. Cancer Epidemiol Biomarkers Prev 26:116-125

Showing the most recent 10 out of 324 publications