The success of marrow transplantation is heavily dependent on the transfusion of blood products and is a situation which provides many opportunities for research in transfusion immunology. In Project IX we have described our research proposals for problems of platelet alloimmunization. In Project III we describe our proposals for the utilization of blood products screened for antibody to cytomegalovirus (CMV) as well as an evaluation of leukocyte-depleted blood products for the prevention of CMV. In this core section we are concerned with mechanisms for deriving research information from clinically necessary transfusion support and plasma modification procedures. We ask support only for key personnel for supervision and data entry where we cannot recover costs from charges but where the work is essential to carrying out the proposed research in individual program projects. These areas include establishing and maintaining data bases containing detailed descriptive information on all blood product transfusions and on the course and outcome of all ABO-incompatible transplants requiring plasma modification or marrow red cell depletion.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
2P01CA018029-12
Application #
3938018
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
12
Fiscal Year
1987
Total Cost
Indirect Cost
Name
Fred Hutchinson Cancer Research Center
Department
Type
DUNS #
075524595
City
Seattle
State
WA
Country
United States
Zip Code
98109
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Deegan, Anthony J; Talebi-Liasi, Faezeh; Song, Shaozhen et al. (2018) Optical coherence tomography angiography of normal skin and inflammatory dermatologic conditions. Lasers Surg Med 50:183-193
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Ogimi, Chikara; Xie, Hu; Leisenring, Wendy M et al. (2018) Initial High Viral Load Is Associated with Prolonged Shedding of Human Rhinovirus in Allogeneic Hematopoietic Cell Transplant Recipients. Biol Blood Marrow Transplant 24:2160-2163
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