Abstract

The Clinical Trials Core assures uniform, highly effective treatment of patients with acute leukemia, providing an appropriate setting for evaluation of the clinical relevance of new information coming from the research projects and the Central Laboratory Core. Highly experienced clinical investigators are available to participate in the design of clinical trials working together with laboratory investigators in the projects. Expert data management and secretarial personnel assure that data generated from the clinical trials are collected in a timely way and entered into the computer to facilitate analyses and regular reporting of results.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA020180-19
Application #
5206935
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
19
Fiscal Year
1996
Total Cost
Indirect Cost

  Publications

Pieters, Rob; Hunger, Stephen P; Boos, Joachim et al. (2011) L-asparaginase treatment in acute lymphoblastic leukemia: a focus on Erwinia asparaginase. Cancer 117:238-49
Kaste, Sue C (2011) Imaging pediatric bone sarcomas. Radiol Clin North Am 49:749-65, vi-vii
Kaste, Sue C; Waszilycsak, George L; McCarville, M Beth et al. (2010) Estimation of potential excess cancer incidence in pediatric 201Tl imaging. AJR Am J Roentgenol 194:245-9
Kaste, S C; Thomas, N A; Rai, S N et al. (2009) Asymptomatic kidney stones in long-term survivors of childhood acute lymphoblastic leukemia. Leukemia 23:104-8
Kaste, Sue C; Metzger, Monika L; Minhas, Anum et al. (2009) Pediatric Hodgkin lymphoma survivors at negligible risk for significant bone mineral density deficits. Pediatr Blood Cancer 52:516-21
Marchese, Victoria G; Connolly, Barbara H; Able, Colleen et al. (2008) Relationships among severity of osteonecrosis, pain, range of motion, and functional mobility in children, adolescents, and young adults with acute lymphoblastic leukemia. Phys Ther 88:341-50
Rai, Shesh N; Hudson, Melissa M; McCammon, Elizabeth et al. (2008) Implementing an intervention to improve bone mineral density in survivors of childhood acute lymphoblastic leukemia: BONEII, a prospective placebo-controlled double-blind randomized interventional longitudinal study design. Contemp Clin Trials 29:711-9
Martin, Mary Beth; Li, Chin-Shang; Rowland, Christopher C et al. (2008) Correlation of bone age, dental age, and chronological age in survivors of childhood acute lymphoblastic leukaemia. Int J Paediatr Dent 18:217-23
Kaste, Sue C; Ahn, Hyunah; Liu, Tiebin et al. (2008) Bone mineral density deficits in pediatric patients treated for sarcoma. Pediatr Blood Cancer 50:1032-8
Kaste, Sue C (2008) Skeletal toxicities of treatment in children with cancer. Pediatr Blood Cancer 50:469-73;discussion 486

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