Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA025803-20
Application #
6102024
Study Section
Project Start
1998-12-01
Project End
2000-11-30
Budget Start
1998-10-01
Budget End
1999-09-30
Support Year
20
Fiscal Year
1999
Total Cost
Indirect Cost
Name
Scripps Research Institute
Department
Type
DUNS #
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Zhang, Xiaohong; Fujii, Hideki; Kishimoto, Hidehiro et al. (2002) Aging leads to disturbed homeostasis of memory phenotype CD8(+) cells. J Exp Med 195:283-93
Camacho, S A; Heath, W R; Carbone, F R et al. (2001) A key role for ICAM-1 in generating effector cells mediating inflammatory responses. Nat Immunol 2:523-9
Ragazzo, J L; Ozaki, M E; Karlsson, L et al. (2001) Costimulation via lymphocyte function-associated antigen 1 in the absence of CD28 ligation promotes anergy of naive CD4+ T cells. Proc Natl Acad Sci U S A 98:241-6
Hernandez, J; Ko, A; Sherman, L A (2001) CTLA-4 blockade enhances the CTL responses to the p53 self-tumor antigen. J Immunol 166:3908-14
Sprent, J; Kishimoto, H (2001) The thymus and central tolerance. Philos Trans R Soc Lond B Biol Sci 356:609-16
Tough, D F; Zhang, X; Sprent, J (2001) An IFN-gamma-dependent pathway controls stimulation of memory phenotype CD8+ T cell turnover in vivo by IL-12, IL-18, and IFN-gamma. J Immunol 166:6007-11
Sprent, J (2001) Burnet oration. T-cell survival and the role of cytokines. Immunol Cell Biol 79:199-206
Kishimoto, H; Sprent, J (2000) The thymus and central tolerance. Clin Immunol 95:S3-7
Tough, D F; Sun, S; Zhang, X et al. (2000) Stimulation of memory T cells by cytokines. Vaccine 18:1642-8
Sprent, J; Zhang, X; Sun, S et al. (2000) T-cell proliferation in vivo and the role of cytokines. Philos Trans R Soc Lond B Biol Sci 355:317-22

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