Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA028852-05
Application #
4691168
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
5
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Yale University
Department
Type
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
Lazo, J S; Schisselbauer, J C; Meandzija, B et al. (1989) Initial single-strand DNA damage and cellular pharmacokinetics of bleomycin A2. Biochem Pharmacol 38:2207-13
Narayanan, R; Jastreboff, M M; Chiu, C F et al. (1988) A method to detect transfected chloramphenicol acetyltransferase gene expression in intact animals. Exp Cell Res 174:297-301
Lin, T S; Guo, J Y; Schinazi, R F et al. (1988) Synthesis and antiviral activity of various 3'-azido analogues of pyrimidine deoxyribonucleosides against human immunodeficiency virus (HIV-1, HTLV-III/LAV). J Med Chem 31:336-40
Lin, T S; Zhang, X H; Wang, Z H et al. (1988) Synthesis and antiviral evaluation of carbocyclic analogues of 2'-azido- and 2'-amino-2'-deoxycytidine. J Med Chem 31:484-6
Hait, W N; Lazo, J S; Chen, D L et al. (1988) Antitumor and toxic effects of combination chemotherapy with bleomycin and a phenothiazine anticalmodulin agent. J Natl Cancer Inst 80:246-50
Jastreboff, M M; Sokoloski, J A; Bertino, J R et al. (1987) Use of electroporation to study the cytotoxic effects of fluorodeoxyuridylate in intact cells. Biochem Pharmacol 36:1345-8
Burke, T G; Morin, M J; Sartorelli, A C et al. (1987) Function of the anthracycline amino group in cellular transport and cytotoxicity. Mol Pharmacol 31:552-6
Lane, P; Vichi, P; Bain, D L et al. (1987) Temperature dependence studies of adriamycin uptake and cytotoxicity. Cancer Res 47:4038-42
Sebti, S M; DeLeon, J C; Lazo, J S (1987) Purification, characterization, and amino acid composition of rabbit pulmonary bleomycin hydrolase. Biochemistry 26:4213-9
Jastreboff, M M; Ito, E; Bertino, J R et al. (1987) Use of electroporation for high-molecular-weight DNA-mediated gene transfer. Exp Cell Res 171:513-7

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