Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA030198-05
Application #
4691301
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
5
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Rockefeller University
Department
Type
DUNS #
071037113
City
New York
State
NY
Country
United States
Zip Code
10065
Liu, C C; Rafii, S; Granelli-Piperno, A et al. (1989) Perforin and serine esterase gene expression in stimulated human T cells. Kinetics, mitogen requirements, and effects of cyclosporin A. J Exp Med 170:2105-18
Montgomery, R R; Cohn, Z A (1989) Endocytic and secretory repertoire of the lipid-loaded macrophage. J Leukoc Biol 45:129-38
Nash, T W; Libby, D M; Horwitz, M A (1988) IFN-gamma-activated human alveolar macrophages inhibit the intracellular multiplication of Legionella pneumophila. J Immunol 140:3978-81
Bhardwaj, N; Horwitz, M A (1988) Interferon-gamma and antibiotics fail to act synergistically to kill Legionella pneumophila in human monocytes. J Interferon Res 8:283-93
Young, J D; Liu, C C; Butler, G et al. (1987) Identification, purification, and characterization of a mast cell-associated cytolytic factor related to tumor necrosis factor. Proc Natl Acad Sci U S A 84:9175-9
Young, J W; Steinman, R M (1987) Mononuclear phagocytes as targets for cytolytic T lymphocytes. J Immunol Methods 100:99-105
Young, J D; Cohn, Z A; Gilula, N B (1987) Functional assembly of gap junction conductance in lipid bilayers: demonstration that the major 27 kd protein forms the junctional channel. Cell 48:733-43
Young, J D; Damiano, A; DiNome, M A et al. (1987) Dissociation of membrane binding and lytic activities of the lymphocyte pore-forming protein (perforin). J Exp Med 165:1371-82
Young, J D; Clark, W R; Liu, C C et al. (1987) A calcium- and perforin-independent pathway of killing mediated by murine cytolytic lymphocytes. J Exp Med 166:1894-9
Young, J D; Cohn, Z A (1987) Cellular and humoral mechanisms of cytotoxicity: structural and functional analogies. Adv Immunol 41:269-332

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