Abstract

This project examines the biomechanical effects of head and neck surgical procedures on swallowing function and on the patient's ability to exert voluntary control over specific aspects of the swallow. A biomechanical analysis will enable us to define the changes in muscle pull created by head and neck surgical procedures and to develop more effective swallow interventions, including surgical reconstruction. Videofluoroscopic swallowing studies of normal subjects and specific groups of surgically treated head and neck cancer patients, collected 3 points in time post surgery, will be quantified biomechanically to identify the ways in which these surgical procedures affect movement patterns of structures in the pharynx during swallow and the patient's ability to produce voluntary swallow rehabilitation maneuvers, as compared to normal subjects. This project utilizes a computerized biomechanical analysis process for the oropharyngeal swallow developed specifically for this purpose. This biomechanical analysis system provides important information on the ways in which structural movements relate to one another and to bolus movement during the physiology of normal oropharyngeal deglutition.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
2P01CA040007-06A1
Application #
3807315
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
6
Fiscal Year
1991
Total Cost
Indirect Cost

  Institution

Name
Northwestern University at Chicago
Department
Type
DUNS #
City
Evanston
State
IL
Country
United States
Zip Code
60201

  Publications

Logemann, Jerilyn A (2014) Critical Factors in the Oral Control Needed for Chewing and Swallowing. J Texture Stud 45:173-179
Pauloski, Barbara Roa; Logemann, Jerilyn A; Rademaker, Alfred W et al. (2013) Effects of enhanced bolus flavors on oropharyngeal swallow in patients treated for head and neck cancer. Head Neck 35:1124-31
Pauloski, Barbara Roa; Rademaker, Alfred W; Lazarus, Cathy et al. (2009) Relationship between manometric and videofluoroscopic measures of swallow function in healthy adults and patients treated for head and neck cancer with various modalities. Dysphagia 24:196-203
Logemann, Jeri A; Pauloski, Barbara Roa; Rademaker, Alfred W et al. (2008) Swallowing disorders in the first year after radiation and chemoradiation. Head Neck 30:148-58
Pauloski, Barbara Roa; Rademaker, Alfred W; Logemann, Jerilyn A et al. (2006) Relationship between swallow motility disorders on videofluorography and oral intake in patients treated for head and neck cancer with radiotherapy with or without chemotherapy. Head Neck 28:1069-76
Daggett, Alicia; Logemann, Jeri; Rademaker, Alfred et al. (2006) Laryngeal penetration during deglutition in normal subjects of various ages. Dysphagia 21:270-4
Smith, Christina H; Logemann, Jeri A; Burghardt, Wesley R et al. (2006) Oral and oropharyngeal perceptions of fluid viscosity across the age span. Dysphagia 21:209-17
Logemann, Jeri A; Rademaker, Alfred W; Pauloski, Barbara Roa et al. (2006) Site of disease and treatment protocol as correlates of swallowing function in patients with head and neck cancer treated with chemoradiation. Head Neck 28:64-73
Logemann, Jeri A; Williams, Rohan B; Rademaker, Alfred et al. (2005) The relationship between observations and measures of oral and pharyngeal residue from videofluorography and scintigraphy. Dysphagia 20:226-31
Waters, Teresa M; Logemann, Jeri A; Pauloski, Barbara Roa et al. (2004) Beyond efficacy and effectiveness: conducting economic analyses during clinical trials. Dysphagia 19:109-19

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