This project proposes to continue the study of surgical effects of reconstruction in oral cancer patients begun in the first 5 years of this project. This study examines the effects of surgical reconstruction for oropharyngeal cancer as a first line rehabilitation strategy in oral cancer patients. To date we have collected data on 186 patients in 25 surgical groups. It is our hypothesis that particular surgical reconstruction can facilitate speech and swallowing or cause a further decrement in function. This project will continue to follow 15 groups or surgically treated oral cancer patients to examine the effects of surgical reconstruction on early and late functional outcomes of speech and swallowing. These 15 groups were selected from the original 25 groups studied in the first 5 years of this project to represent the most frequently used resection/reconstruction categories. Each patient will be followed for 3 months postoperatively. All patients will be studied preoperatively, at 1 month and 3 months postheading. At each of these data collection points, each patient will receive a videofluoroscopic assessment of swallowing and speech, an articulation test and recording of conversational speech for later intelligibility rating.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
2P01CA040007-06A1
Application #
3807316
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
6
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Northwestern University at Chicago
Department
Type
DUNS #
City
Evanston
State
IL
Country
United States
Zip Code
60201
Logemann, Jerilyn A (2014) Critical Factors in the Oral Control Needed for Chewing and Swallowing. J Texture Stud 45:173-179
Pauloski, Barbara Roa; Logemann, Jerilyn A; Rademaker, Alfred W et al. (2013) Effects of enhanced bolus flavors on oropharyngeal swallow in patients treated for head and neck cancer. Head Neck 35:1124-31
Pauloski, Barbara Roa; Rademaker, Alfred W; Lazarus, Cathy et al. (2009) Relationship between manometric and videofluoroscopic measures of swallow function in healthy adults and patients treated for head and neck cancer with various modalities. Dysphagia 24:196-203
Logemann, Jeri A; Pauloski, Barbara Roa; Rademaker, Alfred W et al. (2008) Swallowing disorders in the first year after radiation and chemoradiation. Head Neck 30:148-58
Pauloski, Barbara Roa; Rademaker, Alfred W; Logemann, Jerilyn A et al. (2006) Relationship between swallow motility disorders on videofluorography and oral intake in patients treated for head and neck cancer with radiotherapy with or without chemotherapy. Head Neck 28:1069-76
Daggett, Alicia; Logemann, Jeri; Rademaker, Alfred et al. (2006) Laryngeal penetration during deglutition in normal subjects of various ages. Dysphagia 21:270-4
Smith, Christina H; Logemann, Jeri A; Burghardt, Wesley R et al. (2006) Oral and oropharyngeal perceptions of fluid viscosity across the age span. Dysphagia 21:209-17
Logemann, Jeri A; Rademaker, Alfred W; Pauloski, Barbara Roa et al. (2006) Site of disease and treatment protocol as correlates of swallowing function in patients with head and neck cancer treated with chemoradiation. Head Neck 28:64-73
Logemann, Jeri A; Williams, Rohan B; Rademaker, Alfred et al. (2005) The relationship between observations and measures of oral and pharyngeal residue from videofluorography and scintigraphy. Dysphagia 20:226-31
Waters, Teresa M; Logemann, Jeri A; Pauloski, Barbara Roa et al. (2004) Beyond efficacy and effectiveness: conducting economic analyses during clinical trials. Dysphagia 19:109-19

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