Abstract

The Instrument and Computer Core will support the research projects by providing a broad range of essential hardware and software support services in the form of customized NMR probe design, new instrumentation and upgrades of existing spectrometers, and installation and integration of a new computer network for analysis and archiving of large multidimensional datasets. Centralization of the construction facilities provides for efficient and rapid development new probe and instrument designs.

  Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
2P01CA041078-04
Application #
3812645
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
4
Fiscal Year
1990
Total Cost
Indirect Cost

  Institution

Name
Fox Chase Cancer Center
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19111

  Publications

Lee, Seung-Cheol; Arias-Mendoza, Fernando; Poptani, Harish et al. (2012) Prediction and Early Detection of Response by NMR Spectroscopy and Imaging. PET Clin 7:119-26
Hultman, Kristi L; Raffo, Anthony J; Grzenda, Adrienne L et al. (2008) Magnetic resonance imaging of major histocompatibility class II expression in the renal medulla using immunotargeted superparamagnetic iron oxide nanoparticles. ACS Nano 2:477-84
Stoyanova, Radka; Querec, Troy D; Brown, Truman R et al. (2004) Normalization of single-channel DNA array data by principal component analysis. Bioinformatics 20:1772-84
Stoyanova, Radka; Nicholls, Andrew W; Nicholson, Jeremy K et al. (2004) Automatic alignment of individual peaks in large high-resolution spectral data sets. J Magn Reson 170:329-35
Stoyanova, Radka; Nicholson, Jeremy K; Lindon, John C et al. (2004) Sample classification based on Bayesian spectral decomposition of metabonomic NMR data sets. Anal Chem 76:3666-74
Sajda, Paul; Du, Shuyan; Brown, Truman R et al. (2004) Nonnegative matrix factorization for rapid recovery of constituent spectra in magnetic resonance chemical shift imaging of the brain. IEEE Trans Med Imaging 23:1453-65
Nahum, Alan E; Movsas, Benjamin; Horwitz, Eric M et al. (2003) Incorporating clinical measurements of hypoxia into tumor local control modeling of prostate cancer: implications for the alpha/beta ratio. Int J Radiat Oncol Biol Phys 57:391-401
Stoyanova, R; Brown, T R (2002) NMR spectral quantitation by principal component analysis. III. A generalized procedure for determination of lineshape variations. J Magn Reson 154:163-75
Stoyanova, R; Brown, T R (2001) NMR spectral quantitation by principal component analysis. NMR Biomed 14:271-7
Ochs, M F; Stoyanova, R S; Arias-Mendoza, F et al. (1999) A new method for spectral decomposition using a bilinear Bayesian approach. J Magn Reson 137:161-76

Showing the most recent 10 out of 46 publications