The aims of the Biostatistics Core are to provide statistical and data management support for the projects and cores in this program. Some examples include: 1. Design and analysis of clinical trials; 2. Analysis of correlative studies, including imaging and physiologic 3. Manipulations and their relationships with each other and clinical data; 4. Management of databases; 5. Stochastic modeling and simulation studies; 6. Computational hardware and software support.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA042745-10
Application #
5207344
Study Section
Project Start
Project End
Budget Start
Budget End
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Stauffer, Paul R; van Rhoon, Gerard C (2016) Overview of bladder heating technology: matching capabilities with clinical requirements. Int J Hyperthermia 32:407-16
Juang, Titania; Stauffer, Paul R; Craciunescu, Oana A et al. (2014) Thermal dosimetry characteristics of deep regional heating of non-muscle invasive bladder cancer. Int J Hyperthermia 30:176-83
Inman, Brant A; Stauffer, Paul R; Craciunescu, Oana A et al. (2014) A pilot clinical trial of intravesical mitomycin-C and external deep pelvic hyperthermia for non-muscle-invasive bladder cancer. Int J Hyperthermia 30:171-5
Angele, Martin K; Albertsmeier, Markus; Prix, Niclas J et al. (2014) Effectiveness of regional hyperthermia with chemotherapy for high-risk retroperitoneal and abdominal soft-tissue sarcoma after complete surgical resection: a subgroup analysis of a randomized phase-III multicenter study. Ann Surg 260:749-54; discussion 754-6
Zagar, Timothy M; Vujaskovic, Zeljko; Formenti, Silvia et al. (2014) Two phase I dose-escalation/pharmacokinetics studies of low temperature liposomal doxorubicin (LTLD) and mild local hyperthermia in heavily pretreated patients with local regionally recurrent breast cancer. Int J Hyperthermia 30:285-94
Viglianti, Benjamin L; Dewhirst, Mark W; Boruta, R J et al. (2014) Systemic anti-tumour effects of local thermally sensitive liposome therapy. Int J Hyperthermia 30:385-92
Dewhirst, Mark W; Chi, Jen-Tsan (2013) Understanding the tumor microenvironment and radioresistance by combining functional imaging with global gene expression. Semin Radiat Oncol 23:296-305
Paulides, Margarethus M; Stauffer, Paul R; Neufeld, Esra et al. (2013) Simulation techniques in hyperthermia treatment planning. Int J Hyperthermia 29:346-57
Cao, Yiting; Eble, Joseph M; Moon, Ejung et al. (2013) Tumor cells upregulate normoxic HIF-1? in response to doxorubicin. Cancer Res 73:6230-42
Boss, M Keara; Muradyan, N; Thrall, D E (2013) DCE-MRI: a review and applications in veterinary oncology. Vet Comp Oncol 11:87-100

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