Core C is responsible for the production of clinical grade anti-CD45 BC8 antibody, anti-CD20 1F5(scFv)4-streptavidin fusion protein and anti CD45 BC8(scFv)4-streptavidin fusion proteins. These reagents will be produced, purified and validated in the Biologies Production Facility of the Fred Hutchinson Cancer Research Center. Antibodies and fusion proteins will be produced under current good manufacturing practice (cGMP) conditions and investigational new drug applications (INDs) will be filed with the Food and Drug Administration (FDA).

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA044991-20
Application #
7405448
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2007-05-01
Budget End
2008-04-30
Support Year
20
Fiscal Year
2007
Total Cost
$125,454
Indirect Cost
Name
Fred Hutchinson Cancer Research Center
Department
Type
DUNS #
078200995
City
Seattle
State
WA
Country
United States
Zip Code
98109
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