Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA050507-03
Application #
2093819
Study Section
Special Emphasis Panel (SRC (P1))
Project Start
1994-07-01
Project End
1999-04-30
Budget Start
1996-07-15
Budget End
1997-04-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Thomas Jefferson University
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
061197161
City
Philadelphia
State
PA
Country
United States
Zip Code
19107
Petruk, Svetlana; Black, Kathryn L; Kovermann, Sina K et al. (2013) Stepwise histone modifications are mediated by multiple enzymes that rapidly associate with nascent DNA during replication. Nat Commun 4:2841
Petruk, Svetlana; Sedkov, Yurii; Johnston, Danika M et al. (2012) TrxG and PcG proteins but not methylated histones remain associated with DNA through replication. Cell 150:922-33
Johnston, Danika M; Sedkov, Yurii; Petruk, Svetlana et al. (2011) Ecdysone- and NO-mediated gene regulation by competing EcR/Usp and E75A nuclear receptors during Drosophila development. Mol Cell 44:51-61
Petruk, Svetlana; Sedkov, Yurii; Brock, Hugh W et al. (2007) A model for initiation of mosaic HOX gene expression patterns by non-coding RNAs in early embryos. RNA Biol 4:1-6
Petruk, Svetlana; Sedkov, Yurii; Riley, Kristen M et al. (2006) Transcription of bxd noncoding RNAs promoted by trithorax represses Ubx in cis by transcriptional interference. Cell 127:1209-21
Krajewski, Wladyslaw A; Nakamura, Tatsuya; Mazo, Alexander et al. (2005) A motif within SET-domain proteins binds single-stranded nucleic acids and transcribed and supercoiled DNAs and can interfere with assembly of nucleosomes. Mol Cell Biol 25:1891-9
Canaani, E; Nakamura, T; Rozovskaia, T et al. (2004) ALL-1/MLL1, a homologue of Drosophila TRITHORAX, modifies chromatin and is directly involved in infant acute leukaemia. Br J Cancer 90:756-60
Smith, Sheryl T; Petruk, Svetlana; Sedkov, Yurii et al. (2004) Modulation of heat shock gene expression by the TAC1 chromatin-modifying complex. Nat Cell Biol 6:162-7
Petruk, Svetlana; Sedkov, Yurii; Smith, Sheryl T et al. (2004) Purification and biochemical properties of the Drosophila TAC1 complex. Methods Enzymol 377:255-66
Nakamura, Tatsuya; Mori, Toshiki; Tada, Shinichiro et al. (2002) ALL-1 is a histone methyltransferase that assembles a supercomplex of proteins involved in transcriptional regulation. Mol Cell 10:1119-28

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