The Administration/Biostatistics Core has two major functions. First, it will provide centralized administrative and fiscal management for all research projects and cores associated with the Program Project. These services will involve coordinating the programmatic aspects of the research activities of the participants and include fiscal overview, preparing and assembling yearly Progress Reports, manuscript and report typing, organizing and scheduling meetings and seminar speakers, and the general allocation of resources. The Biostatistics component will provide the bioinformatics necessary for the design and analysis of carcinogenesis experiments, analysis of gene expression array data and dual labeling results as well as general statistical tests. The Administration Core will be headed by Dr. Medina and assisted by Dr. Rosen, and staffed by a full time administrative secretary, Kathy Key. The Biostatistics component will be headed by Dr. Susan Hilsenbeck.
| Medina, Daniel; Kittrell, Frances; Hill, Jamal et al. (2009) Prevention of tumorigenesis in p53-null mammary epithelium by rexinoid bexarotene, tyrosine kinase inhibitor gefitinib, and celecoxib. Cancer Prev Res (Phila) 2:168-74 |
| Medina, D; Kittrell, F S; Tsimelzon, A et al. (2007) Inhibition of mammary tumorigenesis by estrogen and progesterone in genetically engineered mice. Ernst Schering Found Symp Proc :109-26 |
| Caulin, Carlos; Nguyen, Thao; Lang, Gene A et al. (2007) An inducible mouse model for skin cancer reveals distinct roles for gain- and loss-of-function p53 mutations. J Clin Invest 117:1893-901 |
| Goepfert, Thea M; Moreno-Smith, Myrthala; Edwards, David G et al. (2007) Loss of chromosomal integrity drives rat mammary tumorigenesis. Int J Cancer 120:985-94 |
| Rajkumar, Lakshmanaswamy; Kittrell, Frances S; Guzman, Raphael C et al. (2007) Hormone-induced protection of mammary tumorigenesis in genetically engineered mouse models. Breast Cancer Res 9:R12 |
| Ginger, Melanie R; Shore, Amy N; Contreras, Alejandro et al. (2006) A noncoding RNA is a potential marker of cell fate during mammary gland development. Proc Natl Acad Sci U S A 103:5781-6 |
| Sharp, Z Dave; Mancini, Maureen G; Hinojos, Cruz A et al. (2006) Estrogen-receptor-alpha exchange and chromatin dynamics are ligand- and domain-dependent. J Cell Sci 119:4101-16 |
| Medina, Daniel (2005) Mammary developmental fate and breast cancer risk. Endocr Relat Cancer 12:483-95 |
| Ginger, Melanie R; Rosen, Jeffrey M (2003) Pregnancy-induced changes in cell-fate in the mammary gland. Breast Cancer Res 5:192-7 |
| Stenoien, D L; Sen, S; Mancini, M A et al. (2003) Dynamic association of a tumor amplified kinase, Aurora-A, with the centrosome and mitotic spindle. Cell Motil Cytoskeleton 55:134-46 |
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