This core will support all the projects and will provide them with elastograms and sonograms of phantoms and tissues. This will be accomplished by utilizing specialized equipment constructed for this purpose. This equipment allows the acquisition of elastography data under a variety of conditions involving transducers, boundary conditions, applied stress and signal processing. Acquired images and data will be stored on Bernoulli disks and disseminated to the other projects. This core will also perform stress-strain measurements of phantom material produced in Core 9002 by Dr. Hall. Results of these measurements will provide the standard for comparison with elastography studies.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
1P01CA064597-04
Application #
6237489
Study Section
Project Start
1997-08-01
Project End
1998-07-31
Budget Start
1996-10-01
Budget End
1997-09-30
Support Year
4
Fiscal Year
1997
Total Cost
Indirect Cost
City
Houston
State
TX
Country
United States
Zip Code
77225
Thittai, Arun K; Yamal, Jose-Miguel; Ophir, Jonathan (2013) Small breast lesion classification performance using the normalized axial-shear strain area feature. Ultrasound Med Biol 39:543-8
Thittai, Arun K; Yamal, Jose-Miguel; Mobbs, Louise M et al. (2011) Axial-shear strain elastography for breast lesion classification: further results from in vivo data. Ultrasound Med Biol 37:189-97
Thittai, Arun K; Galaz, Belfor; Ophir, Jonathan (2011) Visualization of HIFU-induced lesion boundaries by axial-shear strain elastography: a feasibility study. Ultrasound Med Biol 37:426-33
Thittai, Arun K; Galaz, Belfor; Ophir, Jonathan (2010) Axial-shear strain distributions in an elliptical inclusion model: experimental validation and in vivo examples with implications to breast tumor classification. Ultrasound Med Biol 36:814-20
Patil, Abhay V; Krouskop, Thomas A; Ophir, Jonathan et al. (2008) On the differences between two-dimensional and three-dimensional simulations for assessing elastographic image quality: a simulation study. Ultrasound Med Biol 34:1129-38
Garra, Brian Stephen (2007) Imaging and estimation of tissue elasticity by ultrasound. Ultrasound Q 23:255-68
Hoyt, Kenneth; Forsberg, Flemming; Ophir, Jonathan (2006) Analysis of a hybrid spectral strain estimation technique in elastography. Phys Med Biol 51:197-209
Chandrasekhar, R; Ophir, J; Krouskop, T et al. (2006) Elastographic image quality vs. tissue motion in vivo. Ultrasound Med Biol 32:847-55
Doyley, Marvin M; Srinivasan, Seshadri; Dimidenko, Eugene et al. (2006) Enhancing the performance of model-based elastography by incorporating additional a priori information in the modulus image reconstruction process. Phys Med Biol 51:95-112
Hoyt, Kenneth; Forsberg, Flemming; Ophir, Jonathan (2006) Comparison of shift estimation strategies in spectral elastography. Ultrasonics 44:99-108

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