The facility intends to synthesize 2 grams of oligomer per year for the Program. The oligomer including 1 gram S-DNA, 700 mg normal DNA and 300 mg RNA and special modified oligos. With the installation of the second Expedite Synthesizer we should be able to offer oligonucleotides at costs that will remain stable in the next 4-5 years. The facility's Technical Director, Dr. Xiaolin Zhang, is responsible for quality control of the DNA produced daily.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
1P01CA072765-01A1
Application #
6237791
Study Section
Project Start
1997-09-01
Project End
1998-06-30
Budget Start
1996-10-01
Budget End
1997-09-30
Support Year
1
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Type
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
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Jin, Shenghao; Zhao, Huiwu; Yi, Yan et al. (2010) c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis. J Clin Invest 120:593-606
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