Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA100327-04
Application #
7596856
Study Section
Subcommittee G - Education (NCI)
Project Start
Project End
Budget Start
2008-04-01
Budget End
2009-03-31
Support Year
4
Fiscal Year
2008
Total Cost
$84,625
Indirect Cost
Name
University of Pittsburgh
Department
Type
DUNS #
004514360
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Yang, Chenjie; Ruffner, Melanie A; Kim, Seon-Hee et al. (2012) Plasma-derived MHC class II+ exosomes from tumor-bearing mice suppress tumor antigen-specific immune responses. Eur J Immunol 42:1778-84
Reay, J; Gambotto, A; Robbins, P D (2012) The antitumor effects of adenoviral-mediated, intratumoral delivery of interleukin 23 require endogenous IL-12. Cancer Gene Ther 19:135-43
Zhao, Xi; Bose, Anamika; Komita, Hideo et al. (2012) Vaccines targeting tumor blood vessel antigens promote CD8(+) T cell-dependent tumor eradication or dormancy in HLA-A2 transgenic mice. J Immunol 188:1782-8
Rao, Aparna; Taylor, Jennifer L; Chi-Sabins, Nina et al. (2012) Combination therapy with HSP90 inhibitor 17-DMAG reconditions the tumor microenvironment to improve recruitment of therapeutic T cells. Cancer Res 72:3196-206
Qu, Yanyan; Chen, Lu; Lowe, Devin B et al. (2012) Combined Tbet and IL12 gene therapy elicits and recruits superior antitumor immunity in vivo. Mol Ther 20:644-51
Qu, Y; Taylor, J L; Bose, A et al. (2011) Therapeutic effectiveness of intratumorally delivered dendritic cells engineered to express the pro-inflammatory cytokine, interleukin (IL)-32. Cancer Gene Ther 18:663-73
Lowe, Devin B; Storkus, Walter J (2011) Chronic inflammation and immunologic-based constraints in malignant disease. Immunotherapy 3:1265-74
Zhao, Xi; Bose, Anamika; Komita, Hideo et al. (2011) Intratumoral IL-12 gene therapy results in the crosspriming of Tc1 cells reactive against tumor-associated stromal antigens. Mol Ther 19:805-14
Zhu, Xinmei; Fallert-Junecko, Beth A; Fujita, Mitsugu et al. (2010) Poly-ICLC promotes the infiltration of effector T cells into intracranial gliomas via induction of CXCL10 in IFN-alpha and IFN-gamma dependent manners. Cancer Immunol Immunother 59:1401-9
Lipscomb, Michael W; Taylor, Jennifer L; Goldbach, Cristina J et al. (2010) DC expressing transgene Foxp3 are regulatory APC. Eur J Immunol 40:480-93

Showing the most recent 10 out of 31 publications