? CORE A: ADMINISTRATIVE The purpose of Core A is to coordinate the administrative functions of this Program Project and to foster a highly communicative, collaborative, and enthusiastic atmosphere to promote the science proposed in this inter-disciplinary application. Core A will serve as the nexus of contact between the project/core leaders and all other personnel at Sanford-Burnham Medical Research Institute, Yale University, and Oxford University, as well as with the SAB and NCI/NIH. Core A will provide all coordination of monthly meetings, organize the regular reviews of the projects and cores, maintain contact with external SAB, organize the annual scientific meeting/symposia, invite seminar speakers, and facilitate training of junior scientists. In addition to these responsibilities, the administrative core will also manage the budget, assist in the preparation of publications, progress reports and renewals, as well as develop the Program's webpage.

Public Health Relevance

? CORE A: ADMINISTRATIVE Core A will provide the management of this Program Project grant by serving as the nexus for communication and coordination of all joint activities between program components, the SAB and NCI.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Research Program Projects (P01)
Project #
5P01CA128814-10
Application #
9925078
Study Section
Special Emphasis Panel (ZCA1)
Project Start
Project End
Budget Start
2020-05-01
Budget End
2021-04-30
Support Year
10
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Sanford Burnham Prebys Medical Discovery Institute
Department
Type
DUNS #
020520466
City
La Jolla
State
CA
Country
United States
Zip Code
92037
García-Jiménez, Custodia; Goding, Colin R (2018) Starvation and Pseudo-Starvation as Drivers of Cancer Metastasis through Translation Reprogramming. Cell Metab :
Theodosakis, Nicholas; Langdon, Casey G; Micevic, Goran et al. (2018) Inhibition of isoprenylation synergizes with MAPK blockade to prevent growth in treatment-resistant melanoma, colorectal, and lung cancer. Pigment Cell Melanoma Res :
Senft, Daniela; Qi, Jianfei; Ronai, Ze'ev A (2018) Ubiquitin ligases in oncogenic transformation and cancer therapy. Nat Rev Cancer 18:69-88
Liu, Xiaoni; Zhang, Shang-Min; McGeary, Meaghan K et al. (2018) KDM5B Promotes Drug Resistance by Regulating Melanoma Propagating Cell Subpopulations. Mol Cancer Ther :
Pathria, Gaurav; Scott, David A; Feng, Yongmei et al. (2018) Targeting the Warburg effect via LDHA inhibition engages ATF4 signaling for cancer cell survival. EMBO J 37:
Wang, Jake; Perry, Curtis J; Meeth, Katrina et al. (2017) UV-induced somatic mutations elicit a functional T cell response in the YUMMER1.7 mouse melanoma model. Pigment Cell Melanoma Res 30:428-435
Falletta, Paola; Sanchez-Del-Campo, Luis; Chauhan, Jagat et al. (2017) Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma. Genes Dev 31:18-33
Theodosakis, Nicholas; Micevic, Goran; Langdon, Casey G et al. (2017) p90RSK Blockade Inhibits Dual BRAF and MEK Inhibitor-Resistant Melanoma by Targeting Protein Synthesis. J Invest Dermatol 137:2187-2196
Damsky, W E; Bosenberg, M (2017) Melanocytic nevi and melanoma: unraveling a complex relationship. Oncogene 36:5771-5792
Poothong, Juthakorn; Sopha, Pattarawut; Kaufman, Randal J et al. (2017) IRE1? nucleotide sequence cleavage specificity in the unfolded protein response. FEBS Lett 591:406-414

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