Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Research Program Projects (P01)
Project #
3P01DA008657-02S1
Application #
2121295
Study Section
Drug Abuse Biomedical Research Review Committee (DABR)
Project Start
1994-03-01
Project End
1999-01-31
Budget Start
1995-02-01
Budget End
1996-01-31
Support Year
2
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
University of Arizona
Department
Pharmacology
Type
Schools of Medicine
DUNS #
City
Tucson
State
AZ
Country
United States
Zip Code
85721

  Publications

Bird, M F; Vardanyan, R S; Hruby, V J et al. (2015) Development and characterisation of novel fentanyl-delta opioid receptor antagonist based bivalent ligands. Br J Anaesth 114:646-56
Nair, Padma; Yamamoto, Takashi; Kulkarni, Vinod et al. (2009) Novel bifunctional peptides as opioid agonists and NK-1 antagonists. Adv Exp Med Biol 611:537-8
Martin, T J; Kim, S A; Cannon, D G et al. (2000) Antagonism of delta(2)-opioid receptors by naltrindole-5'-isothiocyanate attenuates heroin self-administration but not antinociception in rats. J Pharmacol Exp Ther 294:975-82
Lashbrook, J M; Ossipov, M H; Hunter, J C et al. (1999) Synergistic antiallodynic effects of spinal morphine with ketorolac and selective COX1- and COX2-inhibitors in nerve-injured rats. Pain 82:65-72
Alfaro-Lopez, J; Okayama, T; Hosohata, K et al. (1999) Exploring the structure-activity relationships of [1-(4-tert-butyl-3'-hydroxy)benzhydryl-4-benzylpiperazine] (SL-3111), a high-affinity and selective delta-opioid receptor nonpeptide agonist ligand. J Med Chem 42:5359-68
Liao, S; Alfaro-Lopez, J; Shenderovich, M D et al. (1998) De novo design, synthesis, and biological activities of high-affinity and selective non-peptide agonists of the delta-opioid receptor. J Med Chem 41:4767-76
Bihm, C C; Williams, C L; Burks, T F (1998) Central actions of endomorphins: new endogenous opioids. Proc West Pharmacol Soc 41:81-3
Ossipov, M H; Lopez, Y; Bian, D et al. (1997) Synergistic antinociceptive interactions of morphine and clonidine in rats with nerve-ligation injury. Anesthesiology 86:196-204
Malatynska, E; Wang, Y; Knapp, R J et al. (1996) Human delta opioid receptor: functional studies on stably transfected Chinese hamster ovary cells after acute and chronic treatment with the selective nonpeptidic agonist SNC-80. J Pharmacol Exp Ther 278:1083-9
Qian, X; Liao, S; Stropova, D et al. (1996) Novel scaffolds for non-peptide mimetics of delta opioid receptor agonists based on peptide leads. Regul Pept 65:79-82

Showing the most recent 10 out of 15 publications